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International Journal of Legal Medicine

, Volume 133, Issue 3, pp 775–776 | Cite as

Genetic polymorphism of 15 autosomal short tandem repeats in Baloch population of Pakistan

  • Aleena Ahmad KhanEmail author
  • Rukhsana Perveen
  • Nadeem Sheikh
  • Babar Hilal Ahmad Abbasi
  • Zunaira Batool
  • Muhammad Shahzad
  • Sana Kaleem
Population Data

Abstract

Allele frequencies and forensic statistical parameters of 15 autosomal short tandem repeats (STRs) were evaluated in 200 genetically unrelated individuals of the Baloch population of Pakistan. Total 155 alleles were observed with allele frequencies ranged from 0.003 to 0.425. Among the 15 STRs, D2S1338 was found to be the most polymorphic and discriminating locus while TPOX was the least polymorphic and discriminating locus. The combined power of discrimination (CPD), combined power of exclusion (CPE), and combined matching probability (CMP) were found to be 0.9999999999999999978, 0.999994252, and 2.14012 × 10−18, respectively. No significant deviation from Hardy–Weinberg Equilibrium (HWE) was observed except for locus D21S11. Additionally, a correlation between previously published data and Baloch population is also presented.

Keywords

Autosomal STRs Genetic polymorphism Forensic Baloch population Pakistan 

Notes

Acknowledgements

We thank all the participants in this study. Also, I would like to thank Ms. Dur-E-Shahwar for her help and cooperation.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

414_2018_1878_MOESM1_ESM.docx (23 kb)
ESM 1 (DOCX 22 kb)
414_2018_1878_MOESM2_ESM.docx (20 kb)
ESM 2 (DOCX 20 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Forensic Services Laboratory, Centre for Applied Molecular BiologyUniversity of the PunjabLahorePakistan
  2. 2.Centre for Advanced Studies in Vaccinology and BiotechnologyUniversity of BalochistanQuettaPakistan

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