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International Journal of Legal Medicine

, Volume 133, Issue 1, pp 99–101 | Cite as

Genetic diversity and haplotype analysis of Guizhou Miao identified with 19 X-chromosomal short tandem repeats

  • Yanyan Han
  • Guanglin He
  • Sheng Gong
  • Junying Chen
  • Zhigang Jiang
  • Pengyu ChenEmail author
Population Data

Abstract

We analyzed Chinese Miao population samples (n = 268) from Guizhou province, Southwest China, with 19 X-chromosomal short tandem repeats (STRs) included in the AGCU X19 amplification kit. The combined PE is 0.999999922 and the combined PDs in males and females are 0.9999999999999999999994 and 0.9999999999998, respectively. The mean paternity exclusion change values are larger than 0.99999996. The HDs in seven linkage groups vary from 0.9324 to 0.9968. Subsequently, comparison among different Chinese populations shows that the substructures of Chinese were significantly influenced by ethno-linguistic rather than geographical boundaries, including most prominently Turkic-speaking and Tibeto-Burman-speaking populations.

Keywords

X-chromosomal STRs Miao population Population genetics Haplotype diversity 

Notes

Funding information

This study received the support of grants from the National Natural Science Foundation of China (No. 81401562), the Fundamental Research Funds for the Central University (2012017yjsy187), the Science and Technology Foundation of Guizhou Province (No. 2013-2313), and the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry (No. 2014-1685).

Compliance with ethical standards

This study had been approved by the institutional review boards at Zunyi Medical University. Informed consent was obtained from volunteers before sample collection.

Competing interests

The authors declare that they have no competing interests.

Supplementary material

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Figure S1

Genetic affinity and differences between the Guizhou Miao and 12 Chinese reference populations based on the genetic variants of 19 X-STRs. (A) Principle component analysis was done by the genetic variances of PCA1 and PCA2. Multidimensional Scaling Plots (B) and Phylogenetic Neighbor-Joining tree (C) were constructed based on Nei’s genetic distances matrix. (PNG 470 kb)

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High Resolution (TIF 3376 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.School of Public HealthZunyi Medical UniversityZunyiChina
  2. 2.Institute of Forensic Medicine, West China School of Basic Medical Sciences & Forensic MedicineSichuan UniversityChengduChina
  3. 3.Criminal Investigation DetachmentQianxinan Prefecture Public Security BureauXingyiChina
  4. 4.Judicial Expertise CenterZunyi City Public Security BureauZunyiChina
  5. 5.Center of Forensic ExpertiseAffiliated Hospital of Zunyi Medical UniversityZunyiChina
  6. 6.School of Forensic MedicineZunyi Medical UniversityZunyiChina

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