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International Journal of Legal Medicine

, Volume 131, Issue 5, pp 1203–1210 | Cite as

How many single nucleotide polymorphisms (SNPs) are needed to replace short tandem repeats (STRs) in forensic applications?

  • Hyo-Jung Lee
  • Jae Won Lee
  • Su Jin Jeong
  • Mira ParkEmail author
Original Article

Abstract

Short tandem repeats (STRs) are the most commonly used forms of genetic information in forensic identification. In recent times, advances in the information on single nucleotide polymorphisms (SNPs) have raised the possibility that these markers could replace the forensically established STRs. In this work, we conducted comparative simulation studies that allowed us to estimate the number of SNPs needed if these markers were used instead of STRs in criminal cases and paternity investigations.

Keywords

Short tandem repeats Single nucleotide polymorphisms 

Notes

Acknowledgements

This research was supported by the Bio & Medical Technology Development Program of the National Research Foundation (NRF) funded by the Ministry of Science, ICT & Future Planning (2012-0009833), the research project for practical use and advancement of forensic DNA analysis of Supreme Prosecutors’ Office, Republic of Korea (1333-304-260, 2014), and the National Research Foundation (NRF) grant funded by the Korea government (MSIP, 2016943438).

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Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Hyo-Jung Lee
    • 1
  • Jae Won Lee
    • 2
  • Su Jin Jeong
    • 2
  • Mira Park
    • 3
    Email author
  1. 1.Product Development HQ, DonaA-STSeoulSouth Korea
  2. 2.Department of StatisticsKorea UniversitySeoulSouth Korea
  3. 3.Department of Preventive MedicineEulji UniversityDaejeonSouth Korea

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