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International Journal of Legal Medicine

, Volume 131, Issue 3, pp 663–666 | Cite as

Genetic polymorphism investigation of the Chinese Yi minority using PowerPlex® Y23 STR amplification system

  • GuangLin He
  • PengYu Chen
  • Xing Zou
  • Xu Chen
  • Feng Song
  • Jing YanEmail author
  • YiPing HouEmail author
Population Data

Abstract

Twenty-three Y-STR loci (DYS576, DYS389I, DYS389 II, DYS448, DYS19, DYS391, DYS481, DYS549, DYS533, DYS438, DYS437, DYS570, DYS635, DYS390, DYS439, DYS392, DYS393, DYS458 DYS456, DYS643, Y-GATA-H4, and DYS385a/b) included in the next-generation PowerPlex® Y23 System were first investigated in 311 unrelated, healthy male individuals from the Yi minority population residing in the Liangshan Yi Autonomous Prefecture, Sichuan, China. A total of 179 alleles and 297 haplotypes were discovered in the Yi group. In total, 285 haplotypes among them were unique, and the remaining 12 haplotypes were observed in two or three individuals. Haplotype discrimination capacity and haplotype diversity were 0.9550 and 0.9989, respectively. Genetic diversity ranged from 0.4550 (DYS437) to 0.9556 (DYS385a/b). Population comparisons between the Yi minority group and 10 Asian meta-populations comprising 58 individual populations were performed. Both multidimensional scaling plots and phylogenetic analyses demonstrated that the genetic structure of the Chinese Yi ethnicity was extremely different compared to Taiwan indigenous inhabitants among 10 Asian meta-populations. Additionally, the genetic structure resemblance of the Yi group was obtained from a geographically close population (Xuanwei Han) or similar language family groups (Thai populations). Besides, our study has demonstrated that the PowerPlex® Y23 System has high polymorphism in a Chinese Yi ethnic population and high discriminatory power for forensic purposes. Population data of the 23 Y-STR obtained from a Yi ethnic population has enriched the Chinese ethnic genetic information.

Keywords

Phylogenetic analysis Forensic genetics Yi ethnicity Y-STR PowerPlex® Y23 system 

Notes

Acknowledgements

We would like to thank all individuals who agreed to take participate in our population investigation. This work was supported by the grants from the National Natural Science Foundation of People’s Republic of China (No. 81571854).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

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Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  1. 1.Department of Forensic Genetics, West China School of Basic Science and Forensic MedicineSichuan University (West China University of Medical Sciences)ChengduChina
  2. 2.Center of Forensic ExpertiseAffiliated Hospital of Zunyi Medical UniversityZunyiChina
  3. 3.Department of Forensic MedicineZunyi Medical UniversityZunyiChina
  4. 4.Department of Forensic Medicine, College of Basic MedicineChongqing Medical UniversityChongqingChina
  5. 5.Department of Clinical Laboratory, the First People’s Hospital of Liangshan Yi Autonomous PrefectureXichangChina

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