International Journal of Legal Medicine

, Volume 130, Issue 6, pp 1509–1511 | Cite as

Population genetics of 23 Y-STR loci in the Mongolian minority population in Inner Mongolia of China

  • Tianzhen Gao
  • Libing Yun
  • Shuang Gao
  • Yan Gu
  • Wang He
  • Haibo Luo
  • Yiping Hou
Population Data


In this study, 23 Y chromosomal STRs (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a, DYS385b, DYS438, DYS439, DYS437, DYS448, DYS456, DYS458, DYS635, YGATAH4, DYS576, DYS481, DYS549, DYS533, DYS570, and DYS643) were investigated in 258 unrelated individuals of Mongolian descent living in the Inner Mongolia Autonomous Region. A total of 233 different haplotypes were found, and 209 of them were unique. Haplotype diversity was 0.9992 and gene diversity ranged from 0.4840 (DYS391) to 0.9679 (DYS385ab). Both R st pairwise analysis and multidimensional scaling plot showed that the genetic structure of the Mongolian population was significantly different from some Chinese ethnic groups and neighboring populations. It is notable that there were null features existing at DYS448 as observed by the PowerPlex® Y23 System, which could be also obtained by sequencing in the Tibetan population.


PowerPlex® Y23 Y chromosome DYS448 Mongolian population 



We would like to thank the volunteers who contributed samples for this study. This work was supported by grants from the Five-Thirteenth National Science and Technology Support Program of China and from the National Natural Science Foundation of China (81330073 and 81571854). This study was also supported by the open fund (KF1408) from Shanghai Key Laboratory of Forensic Medicine (Institute of Forensic Science, Ministry of Justice), China.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

Supplementary material

414_2016_1433_MOESM1_ESM.docx (705 kb)
Supplementary Fig. 1 The location of our sample collection in Inner Mongolia (red colour) on a map of China. (DOCX 705 kb)
414_2016_1433_MOESM2_ESM.docx (188 kb)
Supplementary Fig. 2 The MDS graphs of 16 populations analysed in this study. The plot showing distances based on Rst values calculated with online tool at (DOCX 187 kb)
414_2016_1433_MOESM3_ESM.docx (540 kb)
Supplementary Fig. 3 Electropherograms. (a) Null alleles detected at locus DYS448 in seven individuals with the PowerPlex® Y23 kit. (b) Null alleles detected at locus DYS448 in these seven individuals with the AGCU Database Y24 STR genotyping kit. (DOCX 539 kb)
414_2016_1433_MOESM4_ESM.xls (90 kb)
Supplementary Table 1 23 Y-STR haplotypes of Mongolians from Inner Mongolia Autonomous Region. (XLS 89 kb)
414_2016_1433_MOESM5_ESM.xls (54 kb)
Supplementary Table 2 Allele frequencies and gene diversities of 23 Y-STR loci in 258 unrelated Mongolians from Inner Mongolia Autonomous Region. (XLS 53 kb)
414_2016_1433_MOESM6_ESM.xlsx (12 kb)
Supplementary Table 3 Pairwise R st values (below diagonal) and p values (above diagonal) calculated for the Mongolians and some other Chinese groups and neighboring populations. (XLSX 12 kb)
414_2016_1433_MOESM7_ESM.doc (30 kb)
Supplementary Table 4 Sequence in the relevant flanking and repeat region of the DYS448 locus for null alleles (DOC 30 kb)


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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Tianzhen Gao
    • 1
  • Libing Yun
    • 1
  • Shuang Gao
    • 2
  • Yan Gu
    • 1
  • Wang He
    • 1
  • Haibo Luo
    • 1
  • Yiping Hou
    • 1
  1. 1.Institute of Forensic Medicine, West China School of Basic Science and Forensic MedicineSichuan UniversityChengduPeople’s Republic of China
  2. 2.Institute of Forensic ScienceOrdos Public Security BureauOrdosChina

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