Population genetics of 26 Y-STR loci for the Han ethnic in Hunan province, China
- 265 Downloads
To study the population data of Y-chromosome STRs (Y-STRs) of Han population resided in Hunan province, we analyzed haplotypes of 26 Y-STRs (DYS19, DYS385a/b, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS481, DYS533, DYS549, DYS570, DYS576, DYS635, DYS643, DYS388, DYS449, DYS460, and YGATAH4) in 310 unrelated male individuals using a commercially available Goldeneye® DNA ID 26Y system. The calculated average gene diversity values ranged from 0.4211 to 0.9590 for DYS438 and DYS385a/b loci, respectively. The discriminatory capacity was 96.77 % with 300 observed haplotypes. Population relationships between Hunan Han and eight other populations available from Y-chromosome haplotype reference database (YHRD) were compared. The results showed that the Han population resided in the Hunan district is significantly different from other populations. Our results also indicated that these 26 Y-STR loci were highly genetically polymorphic in the Hunan Han population and of great value in forensic application.
KeywordsGoldeneye® DNA ID 26Y system Haplotypes Y-STRs Population data
This study was supported by the National Natural Science Foundation of China (81201486).
Compliance with ethical standards
The current study was performed in the Department of Forensic Science (Central South University, China) and was approved by the Ethics Committee of Central South University, Xiangya School of Medicine (Approval Code: 201303147).
Conflict of interest
The authors declare that they have no conflict of interest.
- 1.Population Census Office under the State Council Department of Population Employment Statistics National Bureau of Statistics (2012) Tabulation of the 2010 population census of the People’s Republic of China. China Statistics Press, BeijingGoogle Scholar
- 3.Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:12–15Google Scholar
- 4.Nei M (1987) Molecular evolutionary genetics. Columbia University Press, New York, p 178Google Scholar