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International Journal of Legal Medicine

, Volume 130, Issue 2, pp 367–369 | Cite as

Genetic portrait of Tamil non-tribal and Irula tribal population using Y chromosome STR markers

  • Rajshree Raghunath
  • Kamalakshi Krishnamoorthy
  • Lakshmi Balasubramanian
  • Ramkumar Kunka Mohanram
Population Data

Abstract

The 17 Y chromosomal short tandem repeat loci included in the AmpFlSTR® Yfiler™ PCR Amplification Kit were used to analyse the genetic diversity of 517 unrelated males representing the non-tribal and Irula tribal population of Tamil Nadu. A total of 392 unique haplotypes were identified among the 400 non-tribal samples whereas 111 were observed among the 117 Irula tribal samples. Rare alleles for the loci DYS458, DYS635 and YGATAH4.1 were also observed in both population. The haplotype diversity for the non-tribal and Irula tribal population were found to be 0.9999, and the gene diversity ranged from 0.2041 (DYS391) to 0.9612 (DYS385). Comparison of the test population with 26 national and global population using principal coordinate analysis (PCoA) and determination of the genetic distance matrix using phylogenetic molecular analysis indicate a clustering of the Tamil Nadu non-tribal and Irula tribal population away from other unrelated population and proximity towards some Indo-European (IE) and Asian population. Data are available in the Y chromosome haplotype reference database (YHRD) under accession number YA004055 for Tamil non-tribal and YA004056 for the Irula tribal group.

Keywords

Y chromosome short tandem repeats Tamil Nadu Irula tribal Haplotypes Gene diversity Population 

Notes

Acknowledgments

The authors would like to thank all the blood donors who contributed to this study.

Funding

None.

Conflict of interest

The authors declare that they have no competing interests.

Supplementary material

414_2015_1207_MOESM1_ESM.pdf (413 kb)
ESM 1 (PDF 413 kb)

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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Rajshree Raghunath
    • 1
    • 2
  • Kamalakshi Krishnamoorthy
    • 1
  • Lakshmi Balasubramanian
    • 1
    • 2
  • Ramkumar Kunka Mohanram
    • 3
  1. 1.Forensic Sciences DepartmentChennaiIndia
  2. 2.Department of BiotechnologySRM UniversityChennaiIndia
  3. 3.SRM Research InstituteSRM UniversityChennaiIndia

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