To evaluate the utility of Y-STR data for DNA testing in two ethnic populations of Xinjiang province, a sample of 338 subjects (121 Kazakhs and 217 Uighurs) was tested. In the Kazakh and Uighur populations, the haplotype diversity was 0.868 and 0.996, respectively, and the discrimination capacity was 0.5950 and 0.8940, respectively. High numbers of singleton haplotypes were observed among Xinjiang Uighurs, but fewer were found in Kazakhs. Our results were also compared with geographically and linguistically close populations.
Y-STR Kazakh Uighur Gene diversity Polymorphism
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We are deeply thankful for all donors who contributed their DNA sample to this study. This work was supported by the grants from Natural Science Foundation of China (31260267), Heart and Stroke Foundation of Canada, “Tianshan Scholar” Project and Doctor Start funding (BS110120) of Xinjiang University.
Conflict of interest
The authors declare that they have no conflict of interest.
Supplementary Table S3Pairwise genetic distances based on analysis of 7 Y-STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392 and DYS393) between Xinjiang Kazakh and Uighur populations and other 16 populations. P values are shown above, Fst values below the diagonal. (XLS 39 kb)
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