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International Journal of Legal Medicine

, Volume 124, Issue 4, pp 295–300 | Cite as

Seventeen Y-chromosomal short tandem repeat haplotypes in seven groups of population living in Taiwan

  • Hsiao-Lin Hwa
  • Li-Hui Tseng
  • Tsang-Ming Ko
  • Yih-Yuan Chang
  • Hsiang-Yi Yin
  • Yi-Ning Su
  • James Chun-I Lee
ORIGINAL ARTICLE

Abstract

The analysis of Y-chromosome short tandem repeat (Y-STR) loci is a powerful tool in forensic casework. The aim of this study was to present the 17 Y-STR loci haplotype distributions of groups of population living in Taiwan and to demonstrate genetic distances between the groups as well as multidimensional scaling plot based on Y-STR genotype data. Five hundred and fifteen DNA samples from unrelated males of seven groups of population, including Taiwanese Han, two groups of indigenous Taiwanese of Taiwan Island, Tao, mainland Chinese, Filipinos, and a group of people with European, Near Eastern, or South Asian ancestry, were analyzed using a commercial kit that co-amplifies 17 Y-STRs. A total of 471 different haplotypes with 440 unique haplotypes were identified. The overall haplotype diversity was 0.9995 ± 0.0002. High haplotype diversity was observed in six groups of population, except the Tao. These Y-STRs revealed a low discrimination capacity in the Tao population (36.84%), which should be considered in forensic practice. The multidimensional scaling plot of these seven groups of population constructed based on the genetic distances according to 17 Y-STR loci presented a clear patrilineal genetic substructure in the area. Partial Y-STRs profiling reduced the discrimination capacity in most groups of population and distorted the multidimensional scaling plot.

Keywords

Y-chromosome Short tandem repeats Forensic genetics Multidimensional scaling plot 

Notes

Acknowledgments

We would like to thank Ms Hong-Ciao Wan, Ms Pi-Mei Hsu, and Ms Shwu-Fang Li for technical support on DNA extraction. This work was supported by a grant from the College of Medicine, National Taiwan University (NTUCM-9503).

Supplementary material

414_2010_425_MOESM1_ESM.doc (30 kb)
Supplementary Figure S1 The multidimensional scaling plot based on 13 Y-chromosome short tandem repeat loci (DYS385a/b, DYS389I, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS456, DYS458, and Y GATA H4) (DOC 33 kb)
414_2010_425_MOESM2_ESM.doc (29 kb)
Supplementary Figure S2 The multidimensional scaling plot based on seven Y-chromosome short tandem repeat loci (DYS389I, DYS391, DYS 393, DYS439, DYS456, DYS458, and Y GATA H4) (DOC 32 kb)
414_2010_425_MOESM3_ESM.doc (1.1 mb)
Supplementary Table S1 Y-chromosome short tandem repeat haplotypes of seven groups of population (DOC 743 kb)
414_2010_425_MOESM4_ESM.doc (358 kb)
Supplementary Table S2 Allele frequency patterns of 17 Y-chromosome short tandem repeat loci in seven groups of population (DOC 293 kb)

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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Hsiao-Lin Hwa
    • 1
    • 2
    • 3
  • Li-Hui Tseng
    • 3
  • Tsang-Ming Ko
    • 4
  • Yih-Yuan Chang
    • 4
  • Hsiang-Yi Yin
    • 1
  • Yi-Ning Su
    • 3
  • James Chun-I Lee
    • 1
    • 5
  1. 1.Department and Graduate Institute of Forensic Medicine, College of MedicineNational Taiwan UniversityTaipeiTaiwan
  2. 2.Department of Obstetrics and GynecologyNational Taiwan University Hospital and College of Medicine, National Taiwan UniversityTaipeiTaiwan
  3. 3.Department of Medical GeneticsNational Taiwan University HospitalTaipeiTaiwan
  4. 4.Genephile Bioscience LaboratoryTaipeiTaiwan
  5. 5.Institute of Forensic MedicineMinistry of JusticeTaipeiRepublic of China

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