International Journal of Legal Medicine

, Volume 124, Issue 2, pp 91–98

Homogeneity in mitochondrial DNA control region sequences in Swedish subpopulations

  • Andreas O. Tillmar
  • Michael D. Coble
  • Thomas Wallerström
  • Gunilla Holmlund
Original Article


In order to promote mitochondrial DNA (mtDNA) testing in Sweden we have typed 296 Swedish males, which will serve as a Swedish mtDNA frequency database. The tested males were taken from seven geographically different regions representing the contemporary Swedish population. The complete mtDNA control region was typed and the Swedish population was shown to have high haplotype diversity with a random match probability of 0.5%. Almost 47% of the tested samples belonged to haplogroup H and further haplogroup comparison with worldwide populations clustered the Swedish mtDNA data together with other European populations. AMOVA analysis of the seven Swedish subregions displayed no significant maternal substructure in Sweden (FST = 0.002). Our conclusion from this study is that the typed Swedish individuals serve as good representatives for a Swedish forensic mtDNA database. Some caution should, however, be taken for individuals from the northernmost part of Sweden (provinces of Norrbotten and Lapland) due to specific demographic conditions. Furthermore, our analysis of a small sample set of a Swedish Saami population confirmed earlier findings that the Swedish Saami population is an outlier among European populations.


Mitochondrial DNA Sweden Saami Control region Demography 

Supplementary material

414_2009_354_MOESM1_ESM.doc (374 kb)
ESM1 (DOC 374 kb)


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Andreas O. Tillmar
    • 1
  • Michael D. Coble
    • 2
  • Thomas Wallerström
    • 3
  • Gunilla Holmlund
    • 1
  1. 1.Department of Forensic Genetics and Forensic ToxicologyNational Board of Forensic MedicineLinköpingSweden
  2. 2.Armed Forces DNA Identification LaboratoryRockvilleUSA
  3. 3.Department of Archaeology and Religious StudiesNorwegian University of Science and Technology (NTNU)TrondheimNorway

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