International Journal of Legal Medicine

, Volume 123, Issue 2, pp 137–141 | Cite as

Genetic sub-structure in western Mediterranean populations revealed by 12 Y-chromosome STR loci

  • V. Rodríguez
  • C. Tomàs
  • J. J. Sánchez
  • J. A. Castro
  • M. M. Ramon
  • A. Barbaro
  • N. Morling
  • A. Picornell
Original Article


Haplotype and allele frequencies of 12 Y-chromosome short tandem repeat (Y-STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385 a/b, DYS437, DYS438 and DYS439) included in the Powerplex® Y System were determined in seven western Mediterranean populations from Valencia, Majorca, Ibiza (eastern Spain), Sicily and three Calabrian provinces (southern Italy). Amongst the 554 males included in the study, 443 different haplotypes were observed of which 372 were only observed once. The other haplotypes were shared by two to seven men. The overall haplotype diversity was 0.9988 ± 0.0002. These Y-STRs markers showed a low capacity of discrimination (56.3%) in the Ibiza population probably due to genetic drift. Comparisons between the populations studied and other neighbouring populations showed a clear genetic sub-structure in the western Mediterranean area.


Y-STRs Eastern Spain Ibiza Sicily Calabria 



This work was partially supported by grants PRDT-2003-12099 and PRDIB-2006-687872 from the Direcció General de R+D+I (Comunitat Autònoma de les Illes Balears) and by Ellen and Aage Andersen’s Foundation.

Supplementary material

414_2008_302_MOESM1_ESM.doc (42 kb)
Fig. S1 Geographic location of the populations studied. IBZ Ibiza, MAJ Majorca, VAL Valencia, SIC Sicily, RC Reggio Calabria, CAT Catanzaro, CSZ Cosenza (DOC 415 KB
414_2008_302_MOESM2_ESM.doc (222 kb)
Table S1 Allele frequency distribution of the 12 Y-STRs included in the Powerplex® Y kit (Promega) in seven western Mediterranean populations (DOC 434 KB)
414_2008_302_MOESM3_ESM.doc (798 kb)
Table S2 Y-chromosome STR haplotypes in 554 unrelated men from the western Mediterranean region (DOC 127 MB)
414_2008_302_MOESM4_ESM.doc (36 kb)
Table S3 Pairwise comparisons of populations (DOC 365 KB)


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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • V. Rodríguez
    • 1
  • C. Tomàs
    • 2
  • J. J. Sánchez
    • 2
    • 3
  • J. A. Castro
    • 1
  • M. M. Ramon
    • 1
  • A. Barbaro
    • 4
  • N. Morling
    • 2
  • A. Picornell
    • 1
  1. 1.Institut Universitari d’Investigacions en Ciències de la Salut (IUNICS) i Laboratori de Genètica, Departament de BiologiaUniversitat de les Illes BalearsPalma de MallorcaSpain
  2. 2.Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health SciencesUniversity of CopenhagenCopenhagenDenmark
  3. 3.Delegación de CanariasInstituto Nacional de Toxicología y Ciencias ForensesTenerifeSpain
  4. 4.Sezione di Genetica ForenseStudio Indagini Mediche e Forensi (SIMEF)Reggio CalabriaItaly

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