Y-chromosome genetic structure in sub-Apennine populations of Central Italy by SNP and STR analysis
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To define the Y-chromosome genetic structure in Apennine populations, 17 Y-chromosome short tandem repeats (Y-STRs) and 37 Y-single nucleotide polymorphisms (Y-SNPs) were typed in 162 subjects living in the upland area of the Marches (Central Italy). A total number of 155 haplotypes (haplotype diversity was 0.9994) and 14 SNP haplogroups were observed. Testing high-resolution Y-chromosome data sets, e.g. using Yfiler and SNPs, increases the discriminatory capacity in individual identification for forensic purposes. It is also useful in autochthonous population and micro-population studies to highlight the most informative loci for evolutionary aims.
KeywordsY-chromosome Short tandem repeats Single nucleotide polymorphisms Population data Italy
Special thanks go to Dr. M. Piani and to all volunteers. This study was supported by a grant from the Ministero per l’Istruzione, l’Università e la Ricerca (MIUR grant no. 2005064329_002).
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