Allele frequencies of the six miniSTR loci in a population from Japan
- 142 Downloads
- 15 Citations
Abstract
Allele frequencies and forensic parameters for the six miniSTR loci D1S1677, D2S441, D4S2364, D10S1248, D14S1434, and D22S1045 were investigated in a sample of 142 unrelated healthy Japanese individuals. The polymerase chain reaction (PCR) products contained within the six loci were less than 119 bp in size. The frequency distributions in the six short tandem repeat (STR) loci showed no deviations from Hardy–Weinberg equilibrium expectations. The accumulated powers of discrimination and power of exclusion for the six loci were 0.999998 and 0.98, respectively. It was thus considered that due to the small PCR products and the moderate degree of polymorphism, analysis with use of the six miniSTR loci was highly beneficial for the forensic analysis of degraded DNA.
Keywords
MiniSTR Japan Population dataReferences
- 1.Kinjhodzic R, Kubat M, Skavic J (2004) Bosnian population data for the 15 STR loci in the Power Plex 16 kit. Int J Legal Med 118:119–121CrossRefPubMedGoogle Scholar
- 2.Veselinovic I, Kubat M, Furac I, Skavic J, Martinovic klaric I, Tasic M (2004) Allele frequencies of the 15 AmpflSTR Identifiler loci in the population of Vojvodina Province, Serbia and Montenegro. Int J Legal Med 118:184–186CrossRefPubMedGoogle Scholar
- 3.Wiegand P, Kleiber M (2001) Less is more—length reduction of STR amplicons using redesigned primers. Int J Legal Med 114:285–287PubMedCrossRefGoogle Scholar
- 4.Tsukada K, Takayanagi K, Asamura H, Ota M, Fukushima H (2002) Multiplex short tandem repeat typing in degraded samples using newly designed primers for the TH01, TPOX, CSF1PO, and vWA loci. Legal Med 4:239–245CrossRefPubMedGoogle Scholar
- 5.Coble MD, Butler JM (2005) Characterization of new miniSTR loci to aid analysis of degraded DNA. J Forensic Sci 50:43–53CrossRefPubMedGoogle Scholar
- 6.Raymond M, Rousset F (1995) GENEPOP (version 1.2): population genetics software for exact tests and ecumenicism. J Hered 86:248–283Google Scholar