International Journal of Legal Medicine

, Volume 117, Issue 5, pp 306–311 | Cite as

Spanish population data and forensic usefulness of a novel Y-STR set (DYS437, DYS438, DYS439, DYS460, DYS461, GATA A10, GATA C4, GATA H4)

  • María T. Zarrabeitia
  • José A. Riancho
  • Leonor Gusmão
  • María V. Lareu
  • Carolina Sañudo
  • António Amorim
  • Angel Carracedo
Short Communication

Abstract

DNA typing of 8 recently described STRs on the Y chromosome was carried out by means of 2 multiplex amplification reactions for 134 unrelated males from Cantabria, a region in northern Spain. Multiplex 1 included loci DYS460 (GATA A7.1), GATA A10, GATA H4 and DYS439; multiplex 2 included DYS461 (GATA A7.2), GATA C4, DYS437 and DYS438. Haplotype diversity was found to be 99.36%, similar to that obtained with the standard 9-STR set ("minimal haplotype") of the European Y-user group (99.35%). The 13-locus haplotype resulting from the combination of the standard minimal haplotype and the 4-locus multiplex 1 showed a 99.89% diversity. Further inclusion of the 4 loci in multiplex 2 resulted in a haplotype diversity of 99.93%. The combination of the "minimal haplotype" and the multiplex 1 in the present study may be an efficient way of increasing the power of discrimination in forensic cases.

Keywords

Microsatellites Short tandem repeats Y-chromosome Haplotype diversity Population genetics 

Notes

Acknowledgement

Supported in part by a grant from Fundación Marqués de Valdecilla.

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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • María T. Zarrabeitia
    • 1
  • José A. Riancho
    • 2
  • Leonor Gusmão
    • 4
  • María V. Lareu
    • 3
  • Carolina Sañudo
    • 1
  • António Amorim
    • 4
  • Angel Carracedo
    • 3
  1. 1.Unidad de Medicina LegalFacultad de Medicina, Universidad de Cantabria C/Herrera Oria, s/nSantanderSpain
  2. 2.Universidad de CantabriaDepartamento de Medicina InternaSantanderSpain
  3. 3.Universidad de SantiagoInstituto de Medicina Legal
  4. 4.Universidad do PortoInstituto de Patologia e Imunologia MolecularPortoPortugal

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