Chromosoma

, Volume 110, Issue 4, pp 305–312

Whole arm inversions of chromosome 4 in Drosophila species

  • Lynn Podemski
  • Camille Ferrer
  • John Locke
Original Article

DOI: 10.1007/s004120100151

Cite this article as:
Podemski, L., Ferrer, C. & Locke, J. Chromosoma (2001) 110: 305. doi:10.1007/s004120100151

Abstract.

Inversions of genetic segments during the evolution of Drosophila are well documented in the X chromosome and most autosomes, but little attention has been paid to chromosome 4, the smallest autosome or "dot chromosome" present in many Drosophila species. From our previous mapping we have defined probes that mark proximal, intermediate, and distal locations of chromosome 4 in D. melanogaster. In situ hybridizations on salivary gland polytene chromosomes with these probes show that the whole right arm, including genes within cytological region 101EF–102F, is inverted relative to D. simulans. We also used these probes to determine the orientation of the arm of the dot chromosome in nine species of Drosophila, including eight from the melanogaster subfamily. To account for the observed whole arm inversions of chromosome 4 in five of the nine species examined, we propose that three inversion events have occurred during the evolution of these species. These whole arm inversions may explain some of the unusual features of this chromosome.

Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  • Lynn Podemski
    • 1
  • Camille Ferrer
    • 1
  • John Locke
    • 1
  1. 1.Department of Biological Sciences, University of Alberta, Edmonton, Canada AB T6G 2E9

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