Chromosoma

, Volume 116, Issue 1, pp 15–20

The role of SUMO in chromosome segregation

Mini-Review

DOI: 10.1007/s00412-006-0079-z

Cite this article as:
Watts, F.Z. Chromosoma (2007) 116: 15. doi:10.1007/s00412-006-0079-z

Abstract

Chromosome segregation is an essential feature of the eukaryotic cell cycle. Efficient chromosome segregation requires the co-ordination of several cellular processes; some of which involve gross rearrangements of the overall structure of the genetic material. Recent advances in the analysis of the role of SUMO (small ubiquitin-like modifier) and in the identification of SUMO-modified targets indicate that sumoylation is likely to have several key roles in regulating chromosome segregation This mini-review summarises the recently published data concerning the role of SUMO in the processes required for efficient chromosome segregation.

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  1. 1.Genome Damage and Stability Centre, School of Life SciencesUniversity of SussexBrightonUK

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