Radiation and Environmental Biophysics

, Volume 53, Issue 1, pp 151–157 | Cite as

Uranium distribution in broiler organs and possibilities for protection

  • Branislava Mitrović
  • Gordana Vitorović
  • Milijan Jovanović
  • Mirjana Lazarević-Macanović
  • Velibor Andrić
  • Mirjana Stojanović
  • Aleksandra Daković
  • Duško Vitorović
Original Paper


The aim of the present study was to investigate the distribution of uranium (uranyl nitrate hexahydrate, UN) in muscle and organs (kidney, liver, and brain) of broilers, after a 7-day contamination with UN and administration of two different adsorbents (organobentonite and organozeolite). The birds were contaminated during 7 days with 25 mg/UN per day. Adsorbents were given via gastric tube, immediately after contamination with UN. In group 1 that did not receive any adsorbents, histopathological changes in the contaminated broilers were observed in small intestine, liver, and kidney in the form of necrosis of intestinal villi, oedema and cytoplasmic vacuolation of hepatocytes, and dystrophic changes in the kidney tubules epithelium. Organobentonite administered via gastric tube (group 2) reduced uranium distribution by 66 % in kidney, 81 % in liver, and 34 % in brain. In group 3, administration of organozeolite reduced uranium distribution by 67 % in kidney, 68 % in liver, and 49 % in brain. In groups 2 and 3, where the broilers received adsorbents immediately after the UN contamination, no histopathological lesions were observed.


Uranium Toxicity Broilers Adsorbents Organobentonite Organozeolite 



This work was supported by the Ministry of Education, Science and Technological Development of Serbia, in the frame of Project Nos. 31003 and 34103.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Branislava Mitrović
    • 1
  • Gordana Vitorović
    • 1
  • Milijan Jovanović
    • 2
  • Mirjana Lazarević-Macanović
    • 1
  • Velibor Andrić
    • 1
  • Mirjana Stojanović
    • 3
  • Aleksandra Daković
    • 2
  • Duško Vitorović
    • 4
  1. 1.Department of Radiology and Radiation Hygiene, Faculty of Veterinary MedicineUniversity in BelgradeBelgradeSerbia
  2. 2.Department of Veterinary Pathology, Faculty of Veterinary MedicineUniversity in BelgradeBelgradeSerbia
  3. 3.Institute for Technology of Nuclear and Other Mineral Row MaterialsUniversity in BelgradeBelgradeSerbia
  4. 4.Faculty of AgricultureUniversity in BelgradeZemunSerbia

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