Thoracic Air-Leak Syndrome Complicating Allogeneic Hematopoietic Stem-Cell Transplantation
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We report a case of thoracic air-leak syndrome, an extremely rare complication developed after an episode of organizing pneumonia due to graft-vs-host disease in a 19-year-old male. This unusual non-infectious pulmonary complication occurred 527 days after allogeneic HSCT and led to the patient’s death within 1 month due to cardio-respiratory failure. Herein, we highlight chest-imaging aspects which are typical. Early detection by high-resolution chest CT could improve patient management.
KeywordsPneumothorax Pneumomediastinum Air-leak Allogeneic hematopoietic stem-cell transplantation Graft-versus-host disease
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Conflict of interest
The authors declare that they have no conflict of interest.
Informed consent was obtained from parents because the person described in the case report has died.