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Lung

, Volume 194, Issue 3, pp 353–361 | Cite as

The Risk Factors and Characteristics of COPD Among Nonsmokers in Korea: An Analysis of KNHANES IV and V

  • Su Hwan Lee
  • Eu Dong Hwang
  • Ju Eun Lim
  • Sungwoo Moon
  • Young Ae Kang
  • Ji Ye Jung
  • Moo Suk Park
  • Se Kyu Kim
  • Joon Chang
  • Young Sam Kim
  • Song Yee KimEmail author
Article

Abstract

Purpose

Chronic obstructive pulmonary disease (COPD) is increasing in prevalence and mortality. This study evaluated the prevalence, risk factors, characteristics, and health-related quality of life (HRQoL) of COPD among nonsmokers in Korea.

Methods

This was a population-based cross-sectional study using data obtained from the Fourth and Fifth Korean National Health and Nutrition Examination Survey, which was conducted from 2007 to 2011.

Results

A total of 15,063 participants completely answered the questionnaire and performed the spirometry. Among them, 59.6 % were nonsmokers and 40.4 % were smokers. The prevalence of nonsmoker COPD was 7.1 %. On multivariate analysis, age ≥65 years (OR, 2.93; 95 % CI, 2.44–3.51), male sex (OR, 2.98; 95 % CI, 2.40–3.71), living in rural area (OR, 1.26; 95 % CI, 1.05–1.51), lower body mass index (BMI) (<18.5 kg/m2) (OR, 3.00; 95 % CI, 1.78–5.01), self-reported asthma (OR, 2.72; 95 % CI, 2.05–3.60), and self-reported tuberculosis (OR, 4.73; 95 % CI, 3.63–6.17) showed a significantly higher risk of nonsmoker COPD. Analysis of nonsmoker and smoker COPD revealed that there are more females in nonsmoker COPD patients (73.9 vs. 6.9 %, P < 0.001). Nonsmoker COPD patients presented with impaired mobility, pain/discomfort, and anxiety/depression functions as well as a lower mean EuroQol Five-Dimension Questionnaire utility score, which showed HRQoL.

Conclusions

The burden of nonsmoker COPD was considerable. Older age, male sex, lower BMI, self-reported asthma, and self-reported tuberculosis were risk factors for nonsmoker COPD and there were differences between nonsmoker and smoker COPD in terms of sex, comorbidities, and HRQoL.

Keywords

Chronic obstructive pulmonary disease Nonsmoker Never-smoker Quality of life Population study 

Notes

Compliance with Ethical Standards

Conflict of Interest

None.

Supplementary material

408_2016_9871_MOESM1_ESM.docx (17 kb)
Supplementary material 1 (DOCX 16 kb)

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Su Hwan Lee
    • 1
  • Eu Dong Hwang
    • 1
  • Ju Eun Lim
    • 1
  • Sungwoo Moon
    • 1
  • Young Ae Kang
    • 1
  • Ji Ye Jung
    • 1
  • Moo Suk Park
    • 1
  • Se Kyu Kim
    • 1
  • Joon Chang
    • 1
  • Young Sam Kim
    • 1
  • Song Yee Kim
    • 1
    Email author
  1. 1.Division of Pulmonology, Department of Internal Medicine, Severance Hospital, Institute of Chest DiseasesYonsei University College of MedicineSeoulKorea

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