, Volume 191, Issue 2, pp 165–175 | Cite as

Management of Malignant Pleural Effusion



Malignancy is one of the most common causes of pleural effusion. Malignant pleural effusion is defined by the presence of malignant cells in the pleural fluid. Development of malignant pleural effusion usually defines advanced malignancy. Pathophysiology of malignant pleural effusion is not fully understood and may involve complex interactions between the mesothelial and malignant cells. Investigations and management of patients with malignant pleural effusion require a multidisciplinary approach. In this review, current practice for management of patients with malignant pleural effusion will be discussed. In addition, imaging techniques will be covered, including the use of thoracic ultrasound and its role in image-guiding pleural procedures. Moreover, interventional techniques will be described, such as medical thoracoscopy, the use of indwelling pleural catheters, or surgery for investigation and management of malignant pleural effusion.


Malignant Pleural effusion Lung cancer Pleurodesis Thoracoscopy 


Conflict of interest



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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Respiratory Medicine, Hull and East Yorkshire Hospitals NHS Trust, Hull York Medical School, Castle Hill HospitalUniversity of HullEast YorkshireUK

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