, Volume 187, Issue 4, pp 241–244 | Cite as

Silicone Injection Causing Acute Pneumonitis: A Case Series

  • Ana C. Zamora
  • Harold R. Collard
  • Lourdes Barrera
  • Felipe Mendoza
  • W. Richard Webb
  • Guillermo Carrillo


Local and systemic complications following injected silicone have been described, especially after cosmetic procedures by unlicensed practitioners. We report a retrospective case series of acute pneumonitis following silicone injection to the buttock. Medical records, pulmonary function tests, blood arterial gases, chest radiographs, and high-resolution computed tomography scans were reviewed. Five patients with acute pneumonitis after injected silicone were identified. All cases were men with a mean age was 25 years. Three patients had the procedure performed by the same practitioner. The amount of injected silicone ranged from 30 to 500 ml. The onset of clinical symptoms began as early as 24 h after injection to as late as 15 days. All cases had diffuse, peripheral, occasionally wedge-shaped opacities on high-resolution computed tomography. At presentation the mean oxygen saturation was 84%. All were treated with steroids and had clinical resolution of their illness within 1 month of presentation. Injection of silicone can lead to serious pulmonary complications but treatment with steroids seems to be beneficial.


Acute lung injury Corticosteroids Silicone oils Embolism 


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Ana C. Zamora
    • 1
  • Harold R. Collard
    • 2
  • Lourdes Barrera
    • 1
  • Felipe Mendoza
    • 1
  • W. Richard Webb
    • 3
  • Guillermo Carrillo
    • 1
  1. 1.Department of Pulmonary FibrosisInstituto Nacional de Enfermedades Respiratorias “Ismael Cosio Villegas” (INER)Mexico CityMexico
  2. 2.Department of MedicineUniversity of California San FranciscoSan FranciscoUSA
  3. 3.Department of RadiologyUniversity of California San FranciscoSan FranciscoUSA

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