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Diagnostic interview for genetic studies (DIGS): inter-rater and test-retest reliability of the French version

  • M. Preisig
  • Brenda T. Fenton
  • Marie-Louise Matthey
  • Alexandre Berney
  • François Ferrero
Original paper

Abstract

The National Institute of Mental Health developed the semi-structured Diagnostic Interview for Genetic Studies (DIGS) for the assessment of major mood and psychotic disorders and their spectrum conditions. The DIGS was translated into French in a collaborative effort of investigators from sites in France and Switzerland. Inter-rater and test-retest reliability of the French version have been established in a clinical sample in Lausanne. Excellent inter-rater reliability was found for schizophrenia, bipolar disorder, major depression, and unipolar schizoaffective disorder while fair inter-rater reliability was demonstrated for bipolar schizoaffective disorder. Using a six-week test-retest interval, reliability for all diagnoses was found to be fair to good with the exception of bipolar schizoaffective disorder. The lower test-retest reliability was the result of a relatively long test-retest interval that favored incomplete symptom recall. In order to increase reliability for lifetime diagnoses in persons not currently affected, best-estimate procedures using additional sources of diagnostic information such as medical records and reports from relatives should supplement DIGS information in family-genetic studies. Within such a procedure, the DIGS appears to be a useful part of data collection for genetic studies on major mood disorders and schizophrenia in French-speaking populations.

Key words Reliability Psychiatric diagnoses Semi-structured interview Genetic studies 

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Copyright information

© Steinkopff Verlag 1999

Authors and Affiliations

  • M. Preisig
    • 1
  • Brenda T. Fenton
    • 1
  • Marie-Louise Matthey
    • 1
  • Alexandre Berney
    • 1
  • François Ferrero
    • 2
  1. 1.University Department of Adult Psychiatry, Hôpital de Cery, CH-1008 Prilly-Lausanne, SwitzerlandCH
  2. 2.University Hospital of Geneva, Department of Psychiatry, CH-1225 Chêne-Bourg, SwitzerlandCH

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