Exercise and physical activity in mental disorders
Exercise (EX) and physical activity (PA) have been shown to prevent or delay the onset of several mental disorders and to have therapeutic effects in different groups of psychiatric disorders. This review focuses on studies investigating EX as therapeutic intervention in anxiety disorders, affective disorders, eating disorders, schizophrenia, and substance use disorders. Despite EX being discussed as a potential therapy for several decades, adequately powered randomized, controlled trials are sparse in most disorder groups. Nevertheless, evidence points toward disorder-specific benefits that can be induced by EX/PA. Mechanisms of the therapeutic effects of EX/PA are summarized, including metabolic and physiological as well as psychological aspects. Finally, implications for research and therapeutic practice are illustrated.
KeywordsExercise Physical activity Mental disorders Psychiatric disorders Therapy Review
Conflict of interest
The authors declare that they have no conflict of interest.
This supplement was not sponsored by outside commercial interests. It was funded by the German Association for Psychiatry and Psychotherapy (DGPPN).
- 4.Strohle A (2008) Physical activity, exercise, depression and anxiety disorders. J Neural TransmGoogle Scholar
- 5.Helmich I, Latini A, Sigwalt A, Carta MG, Machado S, Velasques B, Ribeiro P, Budde H (2010) Draft for clinical practice and epidemiology in mental health neurobiological alterations induced by exercise and their impact on depressive disorders. Clin Pract Epidemiol Ment Health 6:115–125PubMedCrossRefGoogle Scholar
- 12.Strohle A, Graetz B, Scheel M, Wittmann A, Feller C, Heinz A, Dimeo F (2009) The acute antipanic and anxiolytic activity of aerobic exercise in patients with panic disorder and healthy control subjects. J Psychiatr ResGoogle Scholar
- 20.Lancer R, Motta R, Lancer D (2007) The effect of aerobic exercise on obsessive-compulsive disorder, anxiety, and depression: a preliminary investigation. The Behavior Therapist 30(3):53–62Google Scholar
- 23.Mead GE, Morley W, Campbell P, Greig CA, McMurdo M, Lawlor DA (2009) Exercise for depression. Cochrane Database Syst Rev (3): CD004366Google Scholar
- 27.Laske C, Banschbach S, Stransky E, Bosch S, Straten G, Machann J, Fritsche A, Hipp A, Niess A, Eschweiler GW (2010) Exercise-induced normalization of decreased BDNF serum concentration in elderly women with remitted major depression. Int J Neuropsychopharmacol 13(5):595–602PubMedCrossRefGoogle Scholar
- 28.Bodin T, Martinsen EW (2004) Mood and self-efficacy during acute exercise in clinical depression. A randomized, controlled study. J Sport Exercise Psy 26(4):623–633Google Scholar
- 32.Hays AE, Goss F, Aaron D, Abt K, Friedman E, Gallagher M, et al. (2008) Hormonal and perceptual changes in bipolar subjects after acute aerobic exercise. Med Sci Sports Exerc 40(17)Google Scholar
- 41.Zunker C, Mitchell JE, Wonderlich SA (2010) Exercise interventions for women with anorexia nervosa: A review of the literature. Int J Eat DisordGoogle Scholar
- 42.del Valle MF, Perez M, Santana-Sosa E, Fiuza-Luces C, Bustamante-Ara N, Gallardo C, Villasenor A, Graell M, Morande G, Romo GR, Lopez-Mojares LM, Ruiz JR, Lucia A (2010) Does resistance training improve the functional capacity and well being of very young anorexic patients? A randomized controlled trial. J Adolesc Health 46(4):352–358PubMedCrossRefGoogle Scholar
- 43.Ussher MH, Taylor A, Faulkner G (2008) Exercise interventions for smoking cessation. Cochrane Database Syst Rev (4): CD002295Google Scholar
- 44.Frankel A, Murphy J (1974) Physical fitness and personality in alcoholism. Canonical analysis of measures before and after treatment. Q J Stud Alcohol 35(4 Pt A): 1272-1278Google Scholar
- 47.Brown RA, Abrantes AM, Read JP, Marcus BH, Jakicic J, Strong DR, Oakley JR, Ramsey SE, Kahler CW, Stuart G, Dubreuil ME, Gordon AA (2008) Aerobic exercise for alcohol recovery: rationale, program description, and preliminary findings. Behav ModifGoogle Scholar
- 49.Williams DJ (2000) Exercise and substance abuse treatment: predicting programme completion. Correct Compendium 25(25):4–7Google Scholar
- 58.Weber A (1984) Laufen als Behandlungsmethode—eine experimentelle Untersuchung an Alkoholabhängigen in der Klinik. Suchtgefahren 30:160–167Google Scholar
- 59.Donaghy ME (1997) The investigation of exercise as an adjunct to the treatment and rehabilitation of the problem drinker. Doctoral dissertation, University of Glasgow, GlasgowGoogle Scholar