Risk factors predisposing for recurrent laryngeal nerve palsy following thyroid malignancy surgery: experience from a tertiary oncology centre
- 13 Downloads
Postoperative recurrent laryngeal nerve (RLN) palsy is one of the major morbidities encountered after thyroid surgery. The risk further increases when surgery is performed for thyroid malignancies.
A retrospective study of patients who underwent hemi, total or completion thyroidectomy at our institute between June 2017 to May 2019 were analyzed. We assessed factors that predisposed to the development of RLN palsy.
The study comprised of 228 patients. A total of 400 nerves were at risk. The RLN palsy rate was 6.8% (n = 27). On univariate and multivariate analysis, the risk of RLN palsy was seen most with pT4a tumor (OR = 8.5), gross extra-thyroidal extension (ETE) (OR = 3.5) and tracheo-esophageal groove (TEG) (OR = 2.8) involvement, followed by aggressive histopathology, and central compartment node positivity.
pT4a tumors, gross ETE, and TEG involvement were the leading causes predisposing for the development of RLN palsy in our series.
KeywordsRecurrent laryngeal nerve Papillary thyroid carcinoma Thyroidectomy Central compartment dissection Extra thyroidal extension Tracheo-esophageal groove
Compliance with ethical standards
Conflict of interest
No potential conflicts of interest to disclose for any author.
- 12.Tuttle RM, Haugen B, Perrier ND (2017) Updated American Joint Committee on Cancer/tumor-node-metastasis staging system for differentiated and anaplastic thyroid cancer: what changed and why?. Mary Ann Liebert, New YorkGoogle Scholar
- 13.Čelakovský P et al (2011) Risk factors for recurrent laryngeal nerve palsy after thyroidectomy. Cent Eur J Med 6(3):279–283Google Scholar
- 18.Ooi LL, Soo KC (1992) Tracheo-oesophageal groove clearance in well-differentiated thyroid carcinoma. Ann Acta Med Singapore 21(5):699–700Google Scholar