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Is there a relation between sudden sensorineural hearing loss and white matter lesions?

  • Massimo Fusconi
  • Giuseppe Attanasio
  • Flavia CapitaniEmail author
  • Edoardo Di Porto
  • Davide Diacinto
  • Isotta Musy
  • Massimo Ralli
  • Giovanni Ralli
  • Antonio Greco
  • Marco de Vincentiis
  • Claudio Colonnese
Otology
  • 14 Downloads

Abstract

Purpose

Sudden sensorineural hearing loss (SSNHL) has similarities to conditions with vascular etiologies such as myocardial infarction and cerebral stroke. Thus, it could be considered as an early sign of a vascular disease and not only a specific local condition. Chronic hypoperfusion in the brain districts leads to a chronic ischemic damage, called cerebral small vessel disease (CSVD), detectable with brain magnetic resonance imaging (MRI).

Methods

The authors used CSVD to establish the presence of vascular risk factors in individuals with SSNHL and used the Fazekas score scale to classify them.

Results

Our study showed that individuals with SSNHL aged between 48 and 60 years have 26% more probability to have a Fazekas score higher than 1 compared to the general population. Individuals younger than 28 years showed a statistically significant negative correlation to have a Fazekas score higher than 0. The higher is the Fazekas score, the less is the probability of hearing recovery. The medium hearing-recovery probability is 46%. This decreases by 16% for every increase of score in the Fazekas scale. In the present study, the recovery probability decreased from 80% in individuals younger than 48 years with a score of 0 to 14% in individuals with a Fazekas scores of 3 and 4.

Conclusions

The authors assessed a higher prevalence of CSVD compared to the general population in patients aged between 48 and 60 years with SSNHL. Moreover, they assessed that the presence of CSVD is related to a decreased probability of recovery, as it has already been demonstrated for stroke.

Keywords

Sudden sensorineural hearing loss Cerebral gliosis Brain MRI Vascular risk factors Recover probability 

Notes

Funding

This study was performed without funding.

Compliance with ethical standards

Conflict of interest

All the authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Massimo Fusconi
    • 1
  • Giuseppe Attanasio
    • 1
  • Flavia Capitani
    • 2
    Email author
  • Edoardo Di Porto
    • 3
  • Davide Diacinto
    • 4
  • Isotta Musy
    • 1
  • Massimo Ralli
    • 1
  • Giovanni Ralli
    • 1
  • Antonio Greco
    • 1
  • Marco de Vincentiis
    • 5
  • Claudio Colonnese
    • 6
    • 7
  1. 1.Department of Sense OrgansSapienza University of RomeRomeItaly
  2. 2.Clinic for Ear, Nose and Throat MedicineUniklinik of TuebingenStuttgartGermany
  3. 3.Department of Economics and StatisticsUniversity of Naples Federico II, Complesso Universitario di Monte Sant’AngeloNaplesItaly
  4. 4.Department of Radiological Sciences, Oncology and Anatomo-PathologyUniversity SapienzaRomeItaly
  5. 5.Department of Oral and Maxillofacial SciencesSapienza University of RomeRomeItaly
  6. 6.Department of Neurology and Psichiatry, Neuroradiology SectionUniversity SapienzaRomeItaly
  7. 7.IRCCS NeuromedPozzilliItaly

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