Microcirculation evaluation of facial nerve palsy using laser speckle contrast imaging: a prospective study
- 27 Downloads
Facial nerve palsy (FNP) is a common disease in the otorhinolaryngological department. Besides the main symptom of motionlessness occurring in the ipsilateral facial muscles in FNP, there are other common complaints of numbness, stiffness and tightness in ipsilateral face described by the patients. Based on our pilot study, we further investigated the relevance between these complaints and facial microcirculation.
Function of facial microcirculation was evaluated by laser speckle contrast imaging (LCSI). Facial perfusion was measured in 143 patients with facial nerve palsy (FNP) at the first visit and follow-up visit under the same conditions.
Difference in FNP patients’ facial microvascular perfusions between ipsilateral and contralateral side was significant (P = 0.0002613). Facial perfusion of patients with Bell’s palsy (P = 00089) and facial nerve tumors (P = 0.025110) was significantly decreasing in the ipsilateral side. Improvement of perfusion could be seen after treatment.
A positive correlation of FNP severity and microvascular impairment can be noticed. During treatment, patients’ ipsilateral perfusion could increase. Therefore, this objective method can measure ipsilateral perfusion in the patients with FNP and the ipsilateral microvascular impairment can be detected through this method.
KeywordsOtology Facial nerve Facial palsy Cholesteatoma
The authors would like to acknowledge Jie Wang and Huijie Yu for revising the English language of the manuscript.
- 5.Mahe G, Humeau-Heurtier A, Durand S, Leftheriotis G, Abraham P (2012) Assessment of skin microvascular function and dysfunction with laser speckle contrast imaging Circ. Cardiovasc Imaging 5:155–63Google Scholar
- 6.Braverman IM (1997) The cutaneous microcirculation: ultrastructure and microanatomical organization. Microcirculation 4: 329–340Google Scholar
- 7.Davis MJ, Hill MA, Kuo L (2013) Local regulation of microvascular perfusion. Morgan and Claypool Life Sciences, LondonGoogle Scholar
- 12.Sabine Sartoretti-Schefer, Wichmann W, Valavanis A (1994) Idiopathic, herpetic, and HIV-associated facial nerve palsies: abnormal MR enhancement patterns. Am J Neuroradiol 15: 479–485Google Scholar