European Archives of Oto-Rhino-Laryngology

, Volume 276, Issue 1, pp 277–278 | Cite as

Laryngopharyngeal reflux and benign lesions of the vocal folds

  • Jerome R. LechienEmail author
  • Abdul Latif Hamdan
  • Sven Saussez
Letter to the Editor

Dear Editor,

The impact of laryngopharyngeal reflux (LPR) in the development of benign lesions of the vocal folds (BLVF) is an important and debated topic of two disorders that concern a large number of patients consulting in voice centers. In their published study, Kibar et al. did not find significant upper esophageal sphincter (UES) alterations according to esophageal manometry in a cohort of patients with suspected LPR [1]. Authors consider that these findings cast doubt about the potential role of LPR in the development of BLVF.

The authors used reflux symptom index (RSI) and reflux finding score (RFS) to identify LPR in their patients (without indicative thresholds of LPR) and did not perform multichannel intraluminal impedance-pH monitoring (MII-pH). In the context of a research that aims to study the relationship between LPR and BLVF, this LPR diagnostic approach could be problematic for many reasons. First, symptoms described in RSI are non-specific and can be encountered in...


Laryngopharyngeal Reflux Laryngitis Lesion Vocal fold 



This study (response to the editor) has not received any support from funding agencies.

Compliance with ethical standards

Conflict of interest

The author had no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Jerome R. Lechien
    • 1
    • 2
    • 3
    Email author
  • Abdul Latif Hamdan
    • 4
  • Sven Saussez
    • 1
    • 3
  1. 1.Department of Anatomy and Experimental Oncology, Mons School of Medicine, UMONS Research Institute for Health Sciences and TechnologyUniversity of Mons (UMons)MonsBelgium
  2. 2.Laboratory of Phonetics, Faculty of Psychology, Research Institute for Language Sciences and TechnologyUniversity of Mons (UMons)MonsBelgium
  3. 3.Department of Otorhinolaryngology and Head and Neck Surgery, School of MedicineCHU Saint-Pierre, Université Libre de BruxellesBrusselsBelgium
  4. 4.Department of Otorhinolaryngology and Head and Neck SurgeryAmerican University of Beirut-Medical CenterBeirutLebanon

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