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European Archives of Oto-Rhino-Laryngology

, Volume 276, Issue 1, pp 223–231 | Cite as

Impact of age on elderly patients with oral cancer

  • Akshat Malik
  • Aseem Mishra
  • Prashant Chopda
  • Hitesh Singhvi
  • Sudhir Nair
  • Deepa Nair
  • Sarbani Ghosh Laskar
  • Kumar Prabhash
  • Jai Prakash Agarwal
  • Pankaj ChaturvediEmail author
Head & Neck
  • 66 Downloads

Abstract

Introduction

In this study we have tried to analyze the impact of age on various clinico-pathological parameters, treatment completion and subsequent survival in older patients.

Materials and methods

This is a retrospective analysis of 140 elderly (> 65 years) patients of oral cancer operated between January 2012 and December 2013. The patients were divided into two groups based upon their age that ≤ 70 years and > 70 years.Association of distribution of various clinico-pathological factors between different groups was assessed by using Chi-square test. Survival analysis was done using Kaplan Meir analysis. Univariate and multivariate analysis were performed.

Results

The two groups had similar distribution of various clinico-pathological factors. Disease free survival for the group ≤ 70 and > 70 years was 37.6 months and 36.4 months (p < 0.594). 13.5% and 7.8% patients > 70 years and ≤ 70 years were either advised or received sub-optimal adjuvant therapy (p < 0.002).

Conclusion

There is no difference distribution of various clinico-pathological factors and survival in patients of oral cancer ≤ 70 and > 70 years of age. Age did not affect survival. Majority of patients could complete the adjuvant therapy advised. Still, significantly more number of patients > 70 years could not receive/complete appropriate adjuvant therapy. Thus treatment needs to be tailored keeping in mind the individual’s performance status and the co-morbidities.

Keywords

Oral cancer Geriatric patients Survival Age Adjuvant therapy 

Notes

Acknowledgements

None.

Funding

None.

Compliance with ethical standards

Conflict of interest

The authors declare that there is no conflict of interest.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Akshat Malik
    • 1
  • Aseem Mishra
    • 1
  • Prashant Chopda
    • 1
  • Hitesh Singhvi
    • 1
  • Sudhir Nair
    • 1
  • Deepa Nair
    • 1
  • Sarbani Ghosh Laskar
    • 2
  • Kumar Prabhash
    • 3
  • Jai Prakash Agarwal
    • 2
  • Pankaj Chaturvedi
    • 1
    Email author
  1. 1.Department of Head and Neck OncologyTata Memorial CentreMumbaiIndia
  2. 2.Department of Radiation OncologyTata Memorial CentreMumbaiIndia
  3. 3.Department of Medical OncologyTata Memorial CentreMumbaiIndia

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