European Archives of Oto-Rhino-Laryngology

, Volume 273, Issue 7, pp 1697–1703 | Cite as

Bone conduction hearing in congenital aural atresia

  • Lichun Zhang
  • Na Gao
  • Yanbo Yin
  • Lin Yang
  • Youzhou Xie
  • Ying Chen
  • Peidong Dai
  • Tianyu ZhangEmail author


Previous researches focusing on BC hearing mechanisms proved that the two routes, (1) EAC sound radiation and (2) inertial of ossicular chain, partially contribute to normal BC hearing. Therefore, the BC hearing for those patients with congenital aural atresia should partially decrease theoretically due to their abnormal anatomy. However, there are not many studies which mention these patients’ BC hearing up till now. The objective of this study is to investigate congenital aural atresia patient’s BC hearing by analysis of pre-surgical audiogram and to study their potential BC hearing mechanisms using animal modeling and their ABR measurements. The study methoed involves analyzing 75 patients’ pre-operative audiogram. Then we produced an animal model by surgery to measure their BC hearing threshold changes. Clinical data showed that those patients had some BC hearing loss; and there were 25 cases (25/75, 33.3 %) which present with typical Carhart’s Notch. The animal experiments proved that inertia of ossicular chain contribute to partial BC hearing, which demonstrated that the inertia produced more affects on high frequencies by comparing with low frequencies. The patients with congenital aural atresia present BC hearing loss, which could be mainly ascribed to the absence of inertia of ossicular chain.


Congenital malformation of external and middle ear Bone conduction Air conduction ABR 



The authors thank The Newly Hundred Promising Talents Training Program from Shanghai Municipal Health Bureau (No. XBR2011068) and The Scholarship Award for Promising Scientists from China Ministry of Education in 2011 providing finial support for this research. In addition, the authors want to express their appreciations to Professor Geoffrey A. Manley for his help in revising language for this manuscript.

Compliance with ethical standards

Conflict of interest

We declare that we have no conflict of interest.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Lichun Zhang
    • 1
  • Na Gao
    • 1
  • Yanbo Yin
    • 2
  • Lin Yang
    • 3
  • Youzhou Xie
    • 1
  • Ying Chen
    • 1
  • Peidong Dai
    • 3
  • Tianyu Zhang
    • 1
    Email author
  1. 1.Department of OtorhinolaryngologyFudan University (Formerly Shanghai Medical University)ShanghaiPeople’s Republic of China
  2. 2.Department of AudiologyFudan University (Formerly Shanghai Medical University)ShanghaiPeople’s Republic of China
  3. 3.Research Center, Shanghai Eye, Ear, Nose and Throat HospitalFudan University (Formerly Shanghai Medical University)ShanghaiPeople’s Republic of China

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