European Archives of Oto-Rhino-Laryngology

, Volume 273, Issue 1, pp 63–72 | Cite as

Comparative analysis of preoperative diagnostic values of HRCT and CBCT in patients with histologically diagnosed otosclerotic stapes footplates

  • Péter Révész
  • Balázs Liktor
  • Bálint Liktor
  • István Sziklai
  • Imre Gerlinger
  • Tamás Karosi
Otology
First Online:
Received:
Accepted:

Abstract

This prospective case review was performed with the aim to compare and asses the diagnostic values of cone-beam computed tomography (CBCT) and high-resolution computed tomography (HRCT) in the preoperative evaluation of otosclerosis. A total of 43 patients with histologically confirmed stapedial otosclerosis, who underwent unilateral stapedectomies were analyzed. Preoperative temporal bone CBCT and HRCT scans were performed in all cases. Both CBCT and HRCT imaging were characterized by a slice thickness of 0.4–0.625 mm and multiplanar image reconstruction. Histopathologic examination of the removed stapes footplates was performed in all cases. Findings of CBCT and HRCT were categorized according to the modified Marshall’s grading system (fenestral or retrofenestral lesions). Histopathologic results were correlated with multiplanar reconstructed CBCT and HRCT scans, respectively. Negative control groups for CBCT (n = 36) and HRCT (n = 27) examinations consisted of patients, who underwent CBCT imaging due to various dental disorders or HRCT analysis due to idiopathic sudden sensorineural hearing loss. Histologically active foci of otosclerosis (n = 31, 72 %) were identified by both CBCT and HRCT in all cases with a sensitivity of 100 %. However, CBCT could not detect histologically inactive otosclerosis (n = 12, 23 %; sensitivity 0 %). In contrast, HRCT showed inactive otosclerosis with a sensitivity of 59.3 %. According to CBCT results, no retrofenestral lesions were found and the overall sensitivity for hypodense lesions was 61.37 %. In conclusion, CBCT is a robust imaging method in the detection of histologically active fenestral hypodense foci of otosclerosis with high sensitivity and radiologic specificity. In the light of these results, HRCT still remains the basic imaging method in the preoperative diagnosis of otosclerosis, since it has much greater sensitivity and specificity in the detection of retrofenestral hypodense lesions and histologically inactive otosclerotic foci in the oval window niche.

Keywords

Cone-beam computed tomography Hearing loss High-resolution computed tomography Histopathology Otosclerosis 
This is a preview of subscription content, log in to check access.

Notes

Conflict of interest

Authors declare that they have no conflicts of interest.

References

  1. 1.
    Chole RA, McKenna M (2001) Pathophysiology of otosclerosis. Otol Neurotol 22:249–257PubMedCrossRefGoogle Scholar
  2. 2.
    Parahy C, Linthicum FH Jr (1984) Otosclerosis and otospongiosis: clinical and histological comparisons. Laryngoscope 94:508–512PubMedCrossRefGoogle Scholar
  3. 3.
    Swartz JD, Faerber EN, Wolfson RJ, Marlowe FI (1984) Fenestral otosclerosis: significance of preoperative CT evaluation. Radiology 151:703–707PubMedCrossRefGoogle Scholar
  4. 4.
    Sziklai I, Batta TJ, Karosi T (2009) Otosclerosis: an organ-specific inflammatory disease with sensorineural hearing loss. Eur Arch Otorhinolaryngol 266:1711–1718PubMedCrossRefGoogle Scholar
  5. 5.
    Declau F, van Spaendonck M, Timmermans JP, Michaels L, Liang J, Qiu JP, van de Heyning P (2007) Prevalence of histologic otosclerosis: an unbiased temporal bone study in Caucasians. Adv Otorhinolaryngol 65:6–16PubMedGoogle Scholar
  6. 6.
    Karosi T, Csomor P, Petkó M, Liktor B, Szabó LZ, Pytel J, Jóri J, Sziklai I (2009) Histopathology of nonotosclerotic stapes fixations. Otol Neurotol 30:1058–1066PubMedCrossRefGoogle Scholar
  7. 7.
    Iyer PV, Gristwood RE (1984) Histopathology of the stapes in otosclerosis. Pathology 16:30–38PubMedCrossRefGoogle Scholar
  8. 8.
    Mafee MF, Henrikson GC, Deitch RL, Norouzi P, Kumar A, Kriz R, Valvassori GE (1985) Use of CT in stapedial otosclerosis. Radiology 156:709–714PubMedCrossRefGoogle Scholar
  9. 9.
    Shaffer KA, Haughton VM, Wilson CR (1980) High resolution computed tomography of the temporal bone. Radiology 134:409–414PubMedCrossRefGoogle Scholar
  10. 10.
    Grayeli AB, Yrieix CS, Imauchi Y, Cyna-Gorse F, Ferrary E, Sterkers O (2004) Temporal bone density measurements using CT in otosclerosis. Acta Otolaryngol 124:1136–1140PubMedCrossRefGoogle Scholar
  11. 11.
    Lagleyre S, Sorrentino T, Calmels MN, Shin YJ, Escudé B, Deguine O, Fraysse B (2009) Reliability of high-resolution CT scan in diagnosis of otosclerosis. Otol Neurotol 30:1152–1159PubMedCrossRefGoogle Scholar
  12. 12.
    Naumann IC, Porcellini B, Fisch U (2005) Otosclerosis: incidence of positive findings on high-resolution computed tomography and their correlation to audiological test data. Ann Otol Rhinol Laryngol 114:709–716PubMedCrossRefGoogle Scholar
  13. 13.
    Shin YJ, Fraysse B, Deguine O, Cognard C, Charlet JP, Sévely A (2001) Sensorineural hearing loss and otosclerosis: a clinical and radiologic survey of 437 cases. Acta Otolaryngol 121:200–204PubMedCrossRefGoogle Scholar
  14. 14.
    Marx M, Lagleyre S, Escudé B, Demeslay J, Elhadi T, Deguine O, Fraysse B (2011) Correlations between CT scan findings and hearing thresholds in otosclerosis. Acta Otolaryngol 131:351–357PubMedCrossRefGoogle Scholar
  15. 15.
    Valvassori GE (1993) Imaging of otosclerosis. Otolaryngol Clin North Am 26:359–371PubMedGoogle Scholar
  16. 16.
    Wycherly BJ, Berkowitz F, Noone AM, Kim HJ (2010) Computed tomography and otosclerosis: a practical method to correlate the sites affected to hearing loss. Ann Otol Rhinol Laryngol 119:789–794PubMedCrossRefGoogle Scholar
  17. 17.
    Kiyomizu K, Tono T, Yang D, Haruta A, Kodama T, Komune S (2004) Correlation of CT analysis and audiometry in Japanese otosclerosis. Auris Nasus Larynx 31:125–129PubMedCrossRefGoogle Scholar
  18. 18.
    Karosi T, Csomor P, Sziklai I (2012) The value of HRCT in stapes fixations corresponding to hearing thresholds and histologic findings. Otol Neurotol 33:1300–1307PubMedCrossRefGoogle Scholar
  19. 19.
    Merchant SN, Rosowski JJ, McKenna MJ (2007) Superior semicircular canal dehiscence mimicking otosclerotic hearing loss. Adv Otorhinolaryngol 65:137–145PubMedPubMedCentralGoogle Scholar
  20. 20.
    Patel S, Dawood A, Ford TP, Whaites E (2007) The potential applications of cone beam computed tomography in the management of endodontic problems. Int Endod J 40:818–830PubMedCrossRefGoogle Scholar
  21. 21.
    Small BW (2007) Cone beam computed tomography. Gen Dent 55:179–181PubMedGoogle Scholar
  22. 22.
    Liktor B, Révész P, Csomor P, Gerlinger I, Sziklai I, Karosi T (2014) Diagnostic value of cone-beam CT in histologically confirmed otosclerosis. Eur Arch Otorhinolaryngol 271:2131–2138PubMedCrossRefGoogle Scholar
  23. 23.
    Redfors YD, Gröndahl HG, Hellgren J, Lindfors N, Nilsson I, Möller C (2012) Otosclerosis: anatomy and pathology in the temporal bone assessed by multi-slice and cone-beam CT. Otol Neurotol 33:922–927PubMedGoogle Scholar
  24. 24.
    Rotteveel LJ, Proops DW, Ramsden RT, Saeed SR, van Olphen AF, Mylanus EA (2004) Cochlear implantation in 53 patients with otosclerosis: demographics, computed tomographic scanning, surgery, and complications. Otol Neurotol 25:943–952PubMedCrossRefGoogle Scholar
  25. 25.
    Marshall AH, Fanning N, Symons S, Shipp D, Chen JM, Nedzelski JM (2005) Cochlear implantation in cochlear otosclerosis. Laryngoscope 115:1728–1733PubMedCrossRefGoogle Scholar
  26. 26.
    Lee TC, Aviv RI, Chen JM, Nedzelski JM, Fox AJ, Symons SP (2009) CT grading of otosclerosis. Am J Neuroradiol 30:1435–1439PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Péter Révész
    • 1
  • Balázs Liktor
    • 2
  • Bálint Liktor
    • 3
  • István Sziklai
    • 4
  • Imre Gerlinger
    • 1
  • Tamás Karosi
    • 2
  1. 1.Department of Otolaryngology and Head and Neck Surgery, Clinical CenterUniversity of PécsPécsHungary
  2. 2.Department of Otolaryngology and Head and Neck SurgeryB-A-Z County Hospital and University HospitalMiskolcHungary
  3. 3.Department of Otolaryngology and Head and Neck SurgeryBajcsy-Zsilinszky HospitalBudapestHungary
  4. 4.Department of Otolaryngology and Head and Neck Surgery, Clinical CenterUniversity of DebrecenDebrecenHungary

Personalised recommendations