European Archives of Oto-Rhino-Laryngology

, Volume 272, Issue 3, pp 765–772 | Cite as

Chondrosarcoma of the nasal septum

  • Mauro Magnano
  • Paolo BoffanoEmail author
  • Giacomo Machetta
  • Elisabetta Garibaldi
  • Elena Delmastro
  • Pietro Gabriele
Case Report


Chondrosarcomas are non-epithelial malignant, slow growing tumors that usually involve pelvis, ribs, and long bones of extremities, scapula and sternum. Median age at diagnosis for head and neck chondrosarcomas is in the fourth decade. The etiopathogenesis of chondrosarcomas remains unknown. Treatment of choice is surgical, with adjuvant therapy having a limited role. In fact, radiation therapy and chemotherapy are reserved for residual or recurrent disease and palliation. As for surgery, several surgical procedures have been described. Recently, endoscopic surgery has allowed for the successful and less invasive treatment of inverting papillomas and even nasopharyngeal angiofibromas, lesions previously requiring extended external approaches. The aim of this paper was to present a case of nasal septal chondrosarcoma that was successfully treated with endoscopic surgery and radiation adjuvant therapy.


Chondrosarcoma Nose Septum Tumor Treatment Cancer 


Conflict of interest

Nothing to disclose.


  1. 1.
    Ali A, Gosavi M, Michael R, Mathew J, Kurien M, Korula A (2004) Chondrosarcoma of the nasal septum. Indian J Otolaryngol Head Neck Surg 56(4):314–316PubMedCentralPubMedGoogle Scholar
  2. 2.
    Coppit GL, Eusterman VD, Bartels J, Downey TJ (2002) Endoscopic resection of chondrosarcomas of the nasal septum: a report of two cases. Otolaryngol Head Neck Surg 127(6):569–571CrossRefPubMedGoogle Scholar
  3. 3.
    Downey TJ, Clark SK, Moore DW (2001) Chondrosarcoma of the nasal septum. Otolaryngol Head Neck Surg 125(1):98–100CrossRefPubMedGoogle Scholar
  4. 4.
    Kainuma K, Netsu K, Asamura K, Hayashi K, Takumi Y, Ota H, Usami S (2009) Chondrosarcoma of the nasal septum: a case report. Auris Nasus Larynx 36(5):601–605CrossRefPubMedGoogle Scholar
  5. 5.
    Dass AN, Peh WC, Shek TW, Ho WK (2008) Case 139: nasal septum low-grade chondrosarcoma. Radiology 249(2):714–717CrossRefPubMedGoogle Scholar
  6. 6.
    Yamamoto S, Motoori K, Takano H, Nagata H, Ueda T, Osaka I (2002) Chondrosarcoma of the nasal septum. Skeletal Radiol 31(9):543–546CrossRefPubMedGoogle Scholar
  7. 7.
    Coca-Pelaz A, Rodrigo JP, Triantafyllou A, Hunt JL, Fernández-Miranda JC, Strojan P, de Bree R, Rinaldo A, Takes RP, Ferlito A (2014) Chondrosarcomas of the head and neck. Eur Arch Otorhinolaryngol 271(10):2601–2609PubMedGoogle Scholar
  8. 8.
    Khan MN, Husain Q, Kanumuri VV, Boghani Z, Patel CR, Liu JK, Eloy JA (2013) Management of sinonasal chondrosarcoma: a systematic review of 161 patients. Int Forum Allergy Rhinol 3(8):670–677CrossRefPubMedGoogle Scholar
  9. 9.
    Holliday EB, Frank SJ (2014) Proton radiation therapy for head and neck cancer: a review of the clinical experience to date. Int J Radiat Oncol Biol Phys 89(2):292–302CrossRefPubMedGoogle Scholar
  10. 10.
    Rieken S, Habermehl D, Nikoghosyan A, Jensen A, Haberer T, Jäkel O, Münter MW, Welzel T, Debus J, Combs SE (2011) Assessment of early toxicity and response in patients treated with proton and carbon ion therapy at the Heidelberg ion therapy center using the raster scanning technique. Int J Radiat Oncol Biol Phys 81(5):e793–e801CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Mauro Magnano
    • 1
  • Paolo Boffano
    • 2
    Email author
  • Giacomo Machetta
    • 1
  • Elisabetta Garibaldi
    • 3
  • Elena Delmastro
    • 3
  • Pietro Gabriele
    • 3
  1. 1.Division of OtolaryngologyPinerolo and Rivoli HospitalsPineroloItaly
  2. 2.Private PracticeTurinItaly
  3. 3.Department of RadiotherapyIstituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - FPOTurinItaly

Personalised recommendations