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Prognostic factors of quality of life after transoral laser microsurgery for laryngeal cancer

  • Head and Neck
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Abstract

We aimed to evaluate factors influencing quality of life (QOL) after transoral laser microsurgery (TLM) of laryngeal cancer. Four hundred and one consecutive disease-free patients were evaluated 1 year after treatment using the University of Washington-QOL v4, the SF-12 (short form of SF-36), and a questionnaire about self-rated health status. The importance of age, gender, tumor location, tumor size, tumor stage, neck dissection and adjuvant treatment were evaluated. One year after TLM patients had a good QOL, with only 6 % of patients reporting a worsening in their health status. Radiation therapy (p = 0.000) and neck dissection (p = 0.000) were negative factors for disease-specific QOL, whereas age ≥70 (p = 0.01) was a positive independent factor for mental score of SF-12. Speech was negatively influenced by tumor size (p = 0.001) as was swallowing by age (p = 0.001) and postoperative radiation (p = 0.000). Patients treated with TLM present a good QOL 1 year after surgery. Radiation and neck dissection negatively impact QOL. Elderly patients cope better with their disabilities.

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Authors and Affiliations

  1. Department of Otorhinolaryngology, Hospital Clínic, c/Villarroel 170, 08036, Barcelona, Spain

    Isabel Vilaseca, Manuel Bernal-Sprekelsen, Ruth Him, Eduardo Lehrer & José Luis Blanch

  2. ENT Surgical Oncology Section, Hospital Clínic, Barcelona, Spain

    Isabel Vilaseca & José Luis Blanch

  3. Faculty of Medicine, University of Barcelona, Barcelona, Spain

    Isabel Vilaseca & Manuel Bernal-Sprekelsen

  4. Department of Head and Neck Surgery, Instituto de Oncología Ángel H. Roffo, Buenos Aires, Argentina

    Alexandra Mandry

Authors
  1. Isabel Vilaseca
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  2. Manuel Bernal-Sprekelsen
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  3. Ruth Him
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  4. Alexandra Mandry
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  5. Eduardo Lehrer
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  6. José Luis Blanch
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Correspondence to Isabel Vilaseca.

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Vilaseca, I., Bernal-Sprekelsen, M., Him, R. et al. Prognostic factors of quality of life after transoral laser microsurgery for laryngeal cancer. Eur Arch Otorhinolaryngol 272, 1203–1210 (2015). https://doi.org/10.1007/s00405-014-3030-6

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  • DOI: https://doi.org/10.1007/s00405-014-3030-6

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