European Archives of Oto-Rhino-Laryngology

, Volume 270, Issue 9, pp 2479–2484 | Cite as

Pulmonary rehabilitation after total laryngectomy: a randomized cross-over clinical trial comparing two different heat and moisture exchangers (HMEs)

  • Jesús Herranz
  • María Alvarez Espiño
  • Carolina Ogen Morado


Post-laryngectomy heat and moisture exchanger (HME) use is known to have a beneficial effect on tracheal climate, pulmonary symptoms and related aspects. This study aims to investigate differences in clinical effects between the first and second generation Provox HMEs. The second generation (Provox XtraHME) has better humidification properties than the first generation (Provox HME), and has been shown to further improve tracheal climate. Forty-five laryngectomized patients, who were already using an HME, participated in a prospective, randomized cross-over clinical study in which each HME was used for 6 weeks. Results showed that for most parameters studied, the second generation HME performed equally well or better than the first generation HME. The improvement in tracheal climate translated into patients reporting significantly less tracheal dryness with the second generation than with the first generation (p = 0.039). Using an HME with better humidification properties is related to a reduction in tracheal dryness in our study population.


Total laryngectomy Heat and moisture exchanger Provox HME Pulmonary rehabilitation Quality of life 



The authors would like to acknowledge Atos Medical for providing the HMEs used in this study free of charge.

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Jesús Herranz
    • 1
  • María Alvarez Espiño
    • 1
  • Carolina Ogen Morado
    • 1
  1. 1.Complexo Hospitalario Universitario A CoruñaLa CoruñaSpain

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