European Archives of Oto-Rhino-Laryngology

, Volume 271, Issue 4, pp 689–693 | Cite as

Serum vitamin D levels in children with recurrent otitis media

  • Atilla CayirEmail author
  • Mehmet Ibrahim Turan
  • Ozalkan Ozkan
  • Yasemin Cayir
  • Avni Kaya
  • Salih Davutoglu
  • Behzat Ozkan


The aims of this study were to evaluate serum vitamin D levels in cases of recurrent otitis media and investigate the effect of vitamin D therapy on the risk of re-occurrence of the disease. This prospective study was performed by comparing serum vitamin D levels in children with recurrent otitis media and healthy children. Eighty-four children between 1 and 5 years of age and diagnosed with recurrent otitis media were enrolled as the study group. One hundred-and-eight healthy children with similar demographic characteristics were enrolled as the control group. Patients were divided into groups according to their serum 25(OH) vitamin D levels. In patients with low initial serum vitamin D levels, vitamin D therapy was administered in addition to conventional treatment for otitis media. Mean serum 25(OH) vitamin D level in the study group was 11.4 ± 9.8 ng/mL Serum 25(OH) vitamin D levels were below 20 ng/mL in 69 % (n = 58) of cases in this group. In the control group, mean serum 25(OH) vitamin D level was 29.2 ± 13.9 ng/mL and was below 20 ng/mL in 30 % (n = 32) of cases. Comparison of serum 25(OH) vitamin D levels and PTH in the study and control groups revealed a statistically significant difference (p < 0.05). Treatment was initiated in cases diagnosed with vitamin D deficiency, and patients were followed up in due course. The only episodes detected over the course of 1-year follow-up were one attack in five patients and two attacks in two. We believe that co-administration of supplementary vitamin D together with conventional treatments is appropriate in the management of upper respiratory infections such as otitis media.


Child Otitis media Vitamin D Therapy 



This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

Conflict of interest

All authors declare that they have no conflicts of interest.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Atilla Cayir
    • 1
    Email author
  • Mehmet Ibrahim Turan
    • 2
  • Ozalkan Ozkan
    • 3
  • Yasemin Cayir
    • 4
  • Avni Kaya
    • 1
  • Salih Davutoglu
    • 2
  • Behzat Ozkan
    • 1
  1. 1.Department of Pediatric Endocrinology, Faculty of MedicineAtaturk UniversityErzurumTurkey
  2. 2.Department of Pediatrics, Faculty of MedicineAtaturk UniversityErzurumTurkey
  3. 3.Department of Otolaryngology, Faculty of MedicineAtaturk UniversityErzurumTurkey
  4. 4.Department of Family Medicine, Faculty of MedicineAtaturk UniversityErzurumTurkey

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