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European Archives of Oto-Rhino-Laryngology

, Volume 270, Issue 3, pp 953–957 | Cite as

Concha bullosa surgery and the distribution of human olfactory neuroepithelium

  • Tayfun Apuhan
  • Yavuz Selim Yıldırım
  • Tuğçe Şimşek
  • Fahrettin Yılmaz
  • Fahri Yılmaz
Rhinology

Abstract

In bullous middle turbinate surgery, controversy exists over which side of the bullous middle turbinate should be removed, as the distribution of human olfactory neuroepithelium is unclear. This study evaluated whether the middle turbinate tissue of patients undergoing endoscopic concha bullosa surgery contains functional olfactory epithelium. This prospective clinical study was conducted in tertiary referable center. It detected 70 conchae bullosa in 48 patients with sinonasal symptoms, who underwent paranasal computed tomography (CT) that showed pneumatization of the middle concha. All samples were obtained under general anesthesia. Three samples were obtained from each bullous middle turbinate: one each from the anterior, medial, and lateral portions. The mucosa from each sample was stained with olfactory marker protein (OMP). In total, 210 middle turbinate samples were taken from 48 patients during endoscopic surgery for conchae bullosa. The patients were 22 females and 26 males. Of the 70 conchae bullosa, OMP-stained nerve tissue was found in the lateral, anterior and medial aspects of 57 (81.4 %), 42 (60.0 %) and 23 (32.8 %) of the bullous middle turbinates, respectively. OMP-stained nerve tissue was found in 122 (58.1 %) of the 210 bullous middle turbinate tissue samples. OMP-stained nerve tissue was found on the lateral surface of the bullous middle turbinate more often than the medial surface. Therefore, during the concha bullosa surgery, OMP-stained nerve tissue found at least in the medial part of concha, suggested that the opening of the medial part of middle concha.

Keywords

Concha bullosa surgery Olfactory neuroepithelium Olfactory mucosa Concha bullosa Middle turbinate OMP Endoscopic surgery 

Notes

Conflict of interest

The authors report no conflict of interest.

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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Tayfun Apuhan
    • 1
  • Yavuz Selim Yıldırım
    • 2
  • Tuğçe Şimşek
    • 1
  • Fahrettin Yılmaz
    • 3
  • Fahri Yılmaz
    • 4
  1. 1.Department of Otolaryngology, Faculty of Izzet Baysal MedicineAbant Izzet Baysal UniversityBoluTurkey
  2. 2.Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of MedicineBezmialem Vakif UniversityIstanbulTurkey
  3. 3.Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of MedicineIstanbul Medipol UniversityIstanbulTurkey
  4. 4.Department of Pathology, Faculty of Izzet Baysal MedicineAbant Izzet Baysal UniversityBoluTurkey

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