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European Archives of Oto-Rhino-Laryngology

, Volume 269, Issue 6, pp 1691–1695 | Cite as

The relationship between Bell’s palsy and morphometric aspects of the facial nerve

  • Yoichiro Kondo
  • Hiroshi Moriyama
  • Shuichi Hirai
  • Ning Qu
  • Masahiro Itoh
Head and Neck

Abstract

Epidemiological data of Bell’s palsy (BP) have been reported. For example, the annual incidence of BP is 15–30 per 100,000 persons, with equal numbers of men and women affected, and there is no predilection for either side of the face. However, details of the relationship between BP and morphometric aspects of the facial nerve have not been available in textbooks. We performed a morphometric analysis of human facial nerve fibers and estimated the total number of myelinated axons (TN) and average transverse area of myelinated axons (ATA). The facial nerve showed a significant decrease of TN with increasing age (r = −0.77; p < 0.01), but showed no significant changes of ATA with age (r = −0.01; p = 0.96). We supposed that the TN decrease with age was a factor in the delayed recovery from BP seen in the elderly. Moreover, the TN and ATA showed no significant differences between female and male specimens (p < 0.05), or between the right and left side specimens (p < 0.05). Our present results seem to explain the absence of significant sex and affected side differences in BP.

Keywords

Facial nerve Morphometry Bell’s palsy 

Notes

Acknowledgments

We thank Ms. Ikuko Moriyama for assistance in preparing the manuscript. This work was supported by a Grant-in-aid for Scientific Research B14370007 from the Ministry of Education, Culture, Sports, Science and Technology of Japan. We certify that any affiliations with or involvement (either competitive or amiable) in any organization or entity with a direct financial interest in the subject matter or materials discussed in the manuscript (e.g., employment, consultancies, stockownership, honoraria, expert testimony, etc.). Otherwise, we have no such financial interest. All financial research or project support is identified in an acknowledgment in the manuscript.

Conflict of interest

The authors have nothing to disclose.

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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Yoichiro Kondo
    • 1
  • Hiroshi Moriyama
    • 2
  • Shuichi Hirai
    • 1
  • Ning Qu
    • 1
  • Masahiro Itoh
    • 1
  1. 1.Department of AnatomyTokyo Medical UniversityTokyoJapan
  2. 2.Department of AnatomyShowa University School of MedicineShinagawa-kuJapan

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