Serious spontaneous epistaxis and hypertension in hospitalized patients
- 439 Downloads
The aim of the study was to evaluate the role of hypertension in patients hospitalized for serious spontaneous epistaxis. This 6-year retrospective study was based on 219 patients hospitalized in a University Hospital ENT and Head and Neck surgery department for serious spontaneous epistaxis. The following parameters were recorded: length of hospital stay, history of hypertension, blood pressure (BP) recordings (on admission, during hospitalization and on discharge), epistaxis severity criteria, including medical and/or surgical management of epistaxis (blood transfusion depending on blood count, embolization, surgery), medications affecting clotting. Epistaxis was classified into two groups: serious and severe. No significant differences were observed between the two groups in terms of age, sex ratio, history of epistaxis and BP characteristics including history of hypertension, mean BP on admission, mean arterial pressure on discharge and number of patients in whom BP was difficult to control. Patients with more severe epistaxis had a similar exposure to anticoagulant and platelet antiaggregant medications as patients with less severe epistaxis. Overall, on univariate logistic regression analysis, no factors were independently associated with severity of epistaxis. The pathophysiology of serious spontaneous epistaxis remains to be unclear. It concerns elderly patients (>60–70 years old) with a history of hypertension in about 50% of cases. Serious spontaneous epistaxis may also be the presenting sign of underlying true hypertension in about 43% of patients with no history of hypertension. However, hypertension per se does not appear to be a statistically significant causal factor and/or a factor of severity of serious spontaneous epistaxis.
- 1.Timsit CA, Bouchène K, Olfatpour B, Tsigaridis P, Herman P, Tran Ba Huy P (2001) Etude épidémiologique et clinique portant sur 20 563 patients accueillis à la grande garde d’urgence ORL adulte de Paris Ile de France (Epidemiology and clinical findings in 20, 563 patients attending the Lariboisière Hospital ENT Adult Emergency Clinic, French). Ann Otolaryngol Chir Cervicofac 118:215–224PubMedGoogle Scholar
- 16.Celik T, Iyisoy A, Yuksel UC, Karahatay S, Tan Y, Isik E. A new evidence of end-organ damage in the patients with arterial hypertension: epistaxis? Int J Cardiol 2009; doi:10.1016/j.ijcard.2008.11.090