European Archives of Oto-Rhino-Laryngology

, Volume 269, Issue 2, pp 615–621 | Cite as

A national series of 244 sinonasal cancers in Finland in 1990–2004

  • Petri Koivunen
  • Antti A. Mäkitie
  • Leif Bäck
  • Matti Pukkila
  • Jussi Laranne
  • Ilpo Kinnunen
  • Kalle Aitasalo
  • Reidar Grénman
Head and Neck
First Online:
Received:
Accepted:

Abstract

Sinonasal cancer is still a somewhat controversial entity because most series are single-center studies. The aim of this study was to give more accurate and generalisable information about treatment of the neck and prognosis of sinonasal cancer. Retrospective, population-based, multicentre study. Altogether 244 patients diagnosed in 1990–2004 were evaluated. The 3- and 5-year disease-specific survival (DSS) rates after treatment with curative intent were 68 and 57%, respectively. Regional status at the time of the diagnosis (P < 0.001, log rank) and local recurrence (P = 0.02, log rank) during the follow-up had a statistically significant effect on DSS. Initially 13% of the patients were diagnosed with neck metastasis. The proportion of regional recurrences during the follow-up was 9%, but it did not have a statistically significant impact on DSS (P = 0.68, log rank). Histopathology had no statistically significant impact on survival in this material of 244 patients. In conclusion, routine elective neck treatment of all sinonasal cancer patients is not recommended, but the importance of the treatment of the primary location is emphasised.

Keywords

Sinonasal cancer Treatment Neck dissection Recurrence Histopathology 
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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Petri Koivunen
    • 1
  • Antti A. Mäkitie
    • 2
    • 3
  • Leif Bäck
    • 3
  • Matti Pukkila
    • 4
  • Jussi Laranne
    • 5
  • Ilpo Kinnunen
    • 2
  • Kalle Aitasalo
    • 2
  • Reidar Grénman
    • 2
  1. 1.Department of Otorhinolaryngology-Head and Neck SurgeryOulu University HospitalOuluFinland
  2. 2.Department of Otorhinolaryngology-Head and Neck SurgeryTurku University Hospital and University of TurkuTurkuFinland
  3. 3.Department of Otorhinolaryngology-Head and Neck SurgeryHelsinki University Central Hospital and University of HelsinkiHelsinkiFinland
  4. 4.Department of Otorhinolaryngology-Head and Neck SurgeryKuopio University HospitalKuopioFinland
  5. 5.Department of Otorhinolaryngology-Head and Neck SurgeryTampere University HospitalTampereFinland

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