European Archives of Oto-Rhino-Laryngology

, Volume 265, Issue 5, pp 587–591 | Cite as

Temporal bone central giant-cell granuloma presenting as a serous otitis media

  • Milan Rudic
  • Alexis Bozorg GrayeliEmail author
  • Dominique Cazals-Hatem
  • Françoise Cyna-Gorse
  • Didier Bouccara
  • Olivier Sterkers
Case Report


Central giant cell granuloma is a benign intraosseous lesion that most commonly occurs in the facial bones. Its location in the temporal bone is extremely rare and only 20 cases have been reported in the literature. We report a case of an adult female patient presenting with a right serous otitis media and mastoiditis associated with a mixed hearing loss during 6 months. CT-scan and MRI revealed a temporal bone tumor involving the mastoid, and surrounding the right temporo-mandibular joint. Tumor was totally removed after a canal-wall-down mastoidectomy and middle ear exclusion. Pathology revealed a central giant cell granuloma. Seven months following the surgery there was no evidence of recurrence. Central giant cell granuloma is a rare temporal bone lesion, with non specific clinical and imaging signs but characteristic pathological features. Today, a total surgical removal and regular MRI follow-up is the best management option.


Hearing loss Serous otitis media Giant cell granuloma Temporal bone Benign tumor 


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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Milan Rudic
    • 1
    • 2
    • 5
  • Alexis Bozorg Grayeli
    • 1
    • 2
    Email author
  • Dominique Cazals-Hatem
    • 3
  • Françoise Cyna-Gorse
    • 4
  • Didier Bouccara
    • 1
    • 2
  • Olivier Sterkers
    • 1
    • 2
  1. 1.Department of Otorhinolaryngology Head and Neck Surgery, AP-HPHospital BeaujonClichy CedexFrance
  2. 2.Inserm UNIT-M 867, Faculté Xavier BichatUniversité Paris 7ParisFrance
  3. 3.Department of Pathology, AP-HPHospital BeaujonClichyFrance
  4. 4.Department of Radiology, AP-HPHospital BeaujonClichyFrance
  5. 5.Department of Oto-rhino-laryngology Head and Neck SurgeryGeneral Hospital ZadarZadarCroatia

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