European Archives of Oto-Rhino-Laryngology

, Volume 265, Issue 3, pp 299–302 | Cite as

Changes of pressure and humidity affect olfactory function

  • Michael Kuehn
  • Heiko Welsch
  • Thomas Zahnert
  • Thomas Hummel
Rhinology

Abstract

The present study aimed at investigating the question whether olfactory function changes in relation to barometric pressure and humidity. Using climate chambers, odor threshold and discrimination for butanol were tested in 75 healthy volunteers under hypobaric and hyperbaric, and different humidity conditions. Among other effects, olfactory sensitivity at threshold level, but not suprathreshold odor discrimination, was impaired in a hypobaric compared to a hyperbaric milieu, and thresholds were lower in humid, compared to relatively dry conditions. In conclusion, environmental conditions modulate the sense of smell, and may, consecutively, influence results from olfactory tests.

Keywords

Olfaction Smell Barometric pressure Humidity Environment 

References

  1. 1.
    Bert P (1878) La pression barométrique: recherches de physiologie expérimentale, Masson, ParisGoogle Scholar
  2. 2.
    Ehrenstein WH, Ehrenstein A (1999) Psychophysical methods. In: Windhorst U, Johansson H (eds) Modern techniques in neuroscience research. Springer, Heidelberg, pp 1211–1241Google Scholar
  3. 3.
    Fleisch A, Von Murant A (1944) Klimaphysiologische Untersuchungen in der Schweiz Teil I. Benno Schwabe & Co., BaselGoogle Scholar
  4. 4.
    Fowler B, Grant A (2000) Hearing thresholds acute hypoxia and relationship to slowing in the auditory modality. Aviat Space Environ Med 71:946–949PubMedGoogle Scholar
  5. 5.
    Hummel T, Sekinger B, Wolf S, Pauli E, Kobal G (1997) “Sniffin’ Sticks”: olfactory performance assessed by the combined testing of odor identification, odor discrimination and olfactory threshold. Chem Senses 22:39–52PubMedCrossRefGoogle Scholar
  6. 6.
    Kobal G, Klimek L, Wolfensberger M, Gudziol H, Temmel A, Owen CM, Seeber H, Pauli E, Hummel T (2000) Multicenter investigation of 1,036 subjects using a standardized method for the assessment of olfactory function combining tests of odor identification, odor discrimination, and olfactory thresholds. Eur Arch Otorhinolaryngol 257:205–211PubMedCrossRefGoogle Scholar
  7. 7.
    Kobrick J (1983) Effects of hypoxia on the luminance threshold for target detection. Avia Space Environ Med 53:112–115Google Scholar
  8. 8.
    McAnally KI, Watson B, Martin RL, Singh B (2005) Effect of hypobaric hypoxia on auditory sensity. Aviat Space Environ Med 74:1251–1255Google Scholar
  9. 9.
    Pavlicek V, Schirlo C, Nebel A, Regard M, Koller EA, Brugger P (2005) Cognitive and emotional processing at high altitude. Aviat Space Environ Med 76:28–33PubMedGoogle Scholar
  10. 10.
    Philpott C, Goodenough P, Passant C, Robertson A, Murty G (2004) The effect of temperature, humidity and peak inspiratory nasal flow on olfactory thresholds. Clin Otolaryngol 29:24–31PubMedCrossRefGoogle Scholar
  11. 11.
    Reitan RM (1958) Validity of the trail-making-test. Percept Mot Skills 8:271–276CrossRefGoogle Scholar
  12. 12.
    Stepanek J (2002) Influence of hypobaric hypoxia on the human sense of smell. Thesis (Master of Public Health). The University of Texas Graduate School of Biomedical Sciences, GalvestonGoogle Scholar
  13. 13.
    Virues-Ortega J, Buela-Casal G, Garrido E, Alcazar B (2004) Neuropsychological functioning associated with high-altitude exposure. Neuropsychol Rev 14:197–224PubMedCrossRefGoogle Scholar
  14. 14.
    Watson DB, Martin RL, McAnally KI, Smith SE, Emonson DL (2000) Effect of normobaric hypoxia on auditory sensitivity. Aviat Space Environ Med 64:30–36Google Scholar
  15. 15.
    Weissenborn K, Ruckert N, Hecker H, Manns MP (1998) The number connection tests A and B: interindividual variability and use for the assessment of early hepatic encephalopathy. J Hepatol 28:646PubMedCrossRefGoogle Scholar
  16. 16.
    WMA (1997) World Medical Association: declaration of Helsinki. Recommendations guiding physicians in biomedical research involving human subjects. J Med Assoc 277:925–926CrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Michael Kuehn
    • 1
  • Heiko Welsch
    • 1
  • Thomas Zahnert
    • 2
  • Thomas Hummel
    • 3
  1. 1.Division Aviation PhysiologyGerman Air Force Institute of Aviation MedicineKönigsbrückGermany
  2. 2.Department of OtorhinolaryngologyUniversity of Dresden Medical SchoolDresdenGermany
  3. 3.Smell and Taste Clinic, Department of OtorhinolaryngologyUniversity of Dresden Medical SchoolDresdenGermany

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