European Archives of Oto-Rhino-Laryngology

, Volume 260, Issue 6, pp 312–315

Hybrid tumours of the salivary glands. A report of two cases involving the palate and a review of the literature

  • Luz María Ruíz-Godoy R
  • Adalberto Mosqueda-Taylor
  • Lourdes Suárez-Roa
  • Adela Poitevin
  • Esther Bandala-Sánchez
  • Abelardo Meneses-García


Hybrid tumours are very rare salivary gland lesions composed of two or more different tumoural entities in a single neoplasm that arise within a definite topographical region. In most cases adenoid cystic carcinoma has been the predominant component in these lesions. In this study we describe two patients with hybrid tumours located in the palate, one in a 49-year-old woman and one in a 71-year-old man. The first case involved adenoid cystic carcinoma and mucoepidermoid carcinoma, and the patient in the second case exhibited adenoid cystic carcinoma and epithelial-myoepithelial carcinoma. Both patients were treated with surgery and radiotherapy, and there has been no evidence of recurrence after 13 and 36 months of follow-up, respectively. The recognition of the histologic component with the higher grade of malignancy in every case of hybrid tumour of the salivary glands is a necessary step to determine the biological behaviour and, consequently, to determine the proper therapeutic approach.


Hybrid tumours Salivary glands Carcinoma 


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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • Luz María Ruíz-Godoy R
    • 1
  • Adalberto Mosqueda-Taylor
    • 2
  • Lourdes Suárez-Roa
    • 1
  • Adela Poitevin
    • 3
  • Esther Bandala-Sánchez
    • 4
  • Abelardo Meneses-García
    • 1
  1. 1.Department of PathologyNational Cancer InstituteTlalpanMexico
  2. 2.Department of Health AttentionAutonomous Metropolitan UniversityXochimilcoMexico
  3. 3.Department of RadiotherapyNational Cancer InstituteTlalpanMexico
  4. 4.Department of Experimental PathologyNational Cancer InstituteTlalpanMexico

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