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Archives of Gynecology and Obstetrics

, Volume 300, Issue 6, pp 1633–1636 | Cite as

Comparison of neovaginoplasty using acellular porcine small intestinal submucosa graft or Interceed in patients with Mayer–Rokitansky–Küster–Hauser syndrome

  • Xuyin Zhang
  • Junjun Qiu
  • Jingxin DingEmail author
  • Keqin HuaEmail author
General Gynecology
  • 31 Downloads

Abstract

Objective

To compare using the acellular porcine small intestinal submucosa (SIS) graft or the Interceed in patients with MRKH syndrome undergoing creation of a neovagina.

Methods

In this retrospective study, patients with MRKH syndrome undergoing creation of a neovagina from 2016 to 2018 were retrospectively investigated. Wharton–Sheares–George neovaginoplasty was performed using the acellular porcine SIS graft or the Interceed.

Results

Overall, 67 patients were included for analysis. The operating time, the estimated blood loss and return of bowel activity were similar between the two groups. However, the total cost in the SIS group was significantly higher than that in the Interceed group due to the cost of the SIS graft. The mean length and width of the neovagina were similar between the two groups. However, the incidence of granulation in vaginal apex was higher in the SIS graft group than that in the Interceed group. There was no statistically significant difference in the total FSFI scores between the two groups who became sexually active postoperatively.

Conclusions

Our results demonstrated that Wharton–Sheares–George method provided the patients to have satisfactory sexual intercourse. The Interceed played a role in the reconstruction of neovagina no less than the SIS graft.

Keywords

MRKH syndrome Acellular porcine small intestinal submucosa graft Neovagina 

Notes

Acknowledgements

This study was supported by a grant from the Science and Technology Commission of Shanghai Municipality (Grant No. 17411960900).

Authors’ contribution

KH, JD contributed to the design of the manuscript. XZ, JD helped in writing the manuscript. JQ contributed to the statistics.

Compliance with ethical standards

Conflict of interest

The authors declared that they have no conflict of interest.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Gynecology, Obstetrics and Gynecology HospitalFudan UniversityShanghaiChina

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