Uterus transplantation: advantages and disadvantages of a deceased donor
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First successful livebirth following uterus transplantation (UTx) from a deceased donor was recently reported by Ejzenberg et al. . In 2014, Brännström et al. achieved the first successful delivery after UTx from a live donor . To date, more than 50 UTx procedures have been performed worldwide, leading to more than 10 newborns after UTx from live donors. However, the report of successful livebirth after UTx from a deceased donor increases the potential of UTx for women with uterine factor infertility (UFI).
Most UTx procedures use a uterus from a live donor, but living-to-living UTx is a highly invasive surgery. Brännström et al. perfected their surgical technique in animal experiments for more than 10 years and conducted clinical studies of UTx in many women; however, the time of donor surgery in the first trial was still ~ 10 h and the blood loss was high . This is because an extremely precise surgical procedure is required to remove a part of the deep uterine...
IK wrote this comment. KB, YM and DA revised the manuscript. All authors read and approved the final manuscript.
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Conflict of interest
The authors declare no competing interests.
Human participants or animal experiments
This article does not contain any studies involving human participants or animals.
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