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Uterus transplantation: advantages and disadvantages of a deceased donor

  • Iori KisuEmail author
  • Kouji Banno
  • Yusuke Matoba
  • Daisuke Aoki
News and Views
  • 37 Downloads

Dear Editor,

First successful livebirth following uterus transplantation (UTx) from a deceased donor was recently reported by Ejzenberg et al. [1]. In 2014, Brännström et al. achieved the first successful delivery after UTx from a live donor [2]. To date, more than 50 UTx procedures have been performed worldwide, leading to more than 10 newborns after UTx from live donors. However, the report of successful livebirth after UTx from a deceased donor increases the potential of UTx for women with uterine factor infertility (UFI).

Most UTx procedures use a uterus from a live donor, but living-to-living UTx is a highly invasive surgery. Brännström et al. perfected their surgical technique in animal experiments for more than 10 years and conducted clinical studies of UTx in many women; however, the time of donor surgery in the first trial was still ~ 10 h and the blood loss was high [3]. This is because an extremely precise surgical procedure is required to remove a part of the deep uterine...

Notes

Author contributions

IK wrote this comment. KB, YM and DA revised the manuscript. All authors read and approved the final manuscript.

Compliance with ethical standards

Conflict of interest

The authors declare no competing interests.

Human participants or animal experiments

This article does not contain any studies involving human participants or animals.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Obstetrics and GynecologyKeio University School of MedicineTokyoJapan

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