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Can myometrial thickness/cervical length ratio predict preterm delivery in singleton pregnancies with threatened preterm labor? A prospective study

  • Selen Gürsoy ErzincanEmail author
  • N. Cenk Sayin
  • Selcuk Korkmaz
  • Havva Sutcu
  • Cihan Inan
  • Isil Uzun Cilingir
  • Fusun G. Varol
Maternal-Fetal Medicine
  • 19 Downloads

Abstract

Objective

To investigate whether myometrial thickness (MT) to cervical length (CL) ratio could be used in the prediction of preterm birth (PTB) in singleton pregnancies presented with threatened preterm labor (TPL).

Methods

After 48 h of successful tocolysis, MT was measured transabdominally from the fundal, mid-anterior walls and the lower uterine segment (LUS) in 46 pregnancies presented with TPL. MT measurements were divided into CL, individually. The main outcome was PTB before 37 weeks of gestation.

Results

The patients were divided into two groups as women delivered ≥ 37 weeks (38.68 ± 1.01 weeks) (n = 25) and those delivered < 37 weeks (34.28 ± 2.53 weeks) (n = 21). The mean ± SD CL in the preterm delivery group was significantly shorter than the term delivery group (23.77 ± 9.23 vs 29.91 ± 7.03 mm, p < 0.05). Fundal, mid-anterior or LUS MT values were similar in both groups. However, in those who delivered preterm, the ratios of fundal MT-to-CL (p = 0.026) and mid-anterior MT-to-CL (p = 0.0085) were significantly different compared to those delivered at term. The optimal cutoff values for CL, fundal MT-to-CL and mid-anterior MT-to-CL ratios in predicting PTB were calculated as 31.1 mm, 0.19 and 0.20, respectively. Fundal MT-to-CL ratio predicted preterm delivery with 71% sensitivity, 72% specificity, 68% positive and 75% negative predictive values. For mid-anterior MT-to-CL ratio, respective values were 76, 76, 73 and 79%.

Conclusion

Measurement of MT along with CL may offer a promising method in the management of women presented with TPL.

Keywords

Threatened preterm labor Preterm delivery Cervical length Myometrial thickness 

Notes

Acknowledgements

We thank Ahsen Ozturk for her medical illustration.

Author contributions

SGE project development, data collection, data analysis, manuscript writing. NCS project development, data analysis, manuscript writing, and critical comments. SK statistical analysis. HS data collection. CI data collection. IUC data collection. FGV data collection.

Compliance with ethical standards

Conflict of interest

We declare that we have no conflict of interest.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Division of Perinatology, Department of Obstetrics and Gynecology, Faculty of MedicineTrakya UniversityEdirneTurkey
  2. 2.Department of Biostatistics, Faculty of MedicineTrakya UniversityEdirneTurkey

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