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Archives of Gynecology and Obstetrics

, Volume 290, Issue 4, pp 803–806 | Cite as

Ovary hyperstimulation syndrome accompanying molar pregnancy: case report and review of the literature

  • Hirotada Suzuki
  • Shigeki Matsubara
  • Shin-ichiro Uchida
  • Akihide Ohkuchi
Review

Abstract

Purpose

To describe a naturally conceived woman with ovary hyperstimulation syndrome (OHSS) accompanying molar pregnancy and review the literature on this condition.

Methods

We report a 31-year-old 2 parous naturally conceived woman with OHSS accompanying partial molar pregnancy. Dilatation and evacuation (D&E) were performed at 10 weeks of gestation. The signs and symptoms of OHSS were the severest on day 8 after D&E, when hCG had already decreased. This case is reported in detail. We also review the literature.

Results

A literature search yielded seven cases of this condition. Any type of molar pregnancy, i.e., complete, partial, or invasive, can accompany OHSS. The initial manifestation of OHSS occurred at a median of the 12th week of gestation (range 7–16), which may be later compared with OHSS caused by ovulation induction. In all cases, OHSS aggravated after D&E.

Conclusions

We must be aware that OHSS can occur during molar pregnancy, and can be exacerbated after D&E.

Keywords

Dilatation and evacuation Human chorionic gonadotropin Molar pregnancy OHSS Ovary hyperstimulation syndrome 

Notes

Conflict of interest

We declare no conflicts of interest.

Patient anonymity

Preserved.

Informed consent

Obtained.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Hirotada Suzuki
    • 1
  • Shigeki Matsubara
    • 1
  • Shin-ichiro Uchida
    • 1
  • Akihide Ohkuchi
    • 1
  1. 1.Department of Obstetrics and GynecologyJichi Medical UniversityShimotsukeJapan

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