Archives of Gynecology and Obstetrics

, Volume 287, Issue 5, pp 919–936

Meta-analysis of the efficacy and safety of the application of adjuvant material in the repair of anterior vaginal wall prolapsed

  • Hu Min
  • Hong Li
  • Li Bingshu
  • Cheng Yanxiang
  • Chen Lu
  • Sun Qing
  • Zhu Xuejiao
  • Wu Wenying
  • Wu Debin
  • Hong Shasha
  • Ding Wenjuan
  • Min Jie
  • Zhang Xiaohong
  • Guo Wenjun
  • Chen Jianhua
  • Liu Qian
  • Liu Yuling
General Gynecology

DOI: 10.1007/s00404-012-2626-6

Cite this article as:
Min, H., Li, H., Bingshu, L. et al. Arch Gynecol Obstet (2013) 287: 919. doi:10.1007/s00404-012-2626-6

Abstract

Introduction

This study is a meta-analysis of the efficacy and safety of the application of adjuvant material in the repair of anterior vaginal wall prolapse and a sub-category analysis of the use of nonabsorbable synthetic mesh, biological graft and absorbable synthetic mesh.

Method

Pubmed, Embase and Ovid databases were searched for published randomized controlled trials from 1980 to February 2012 on the treatment of anterior vaginal wall prolapse with adjuvant materials. A comprehensive meta-analysis applying Revman5.1 analysis software was performed.

Results

A total of 20 randomized controlled trials including 2,313 participants were recognized. The result showed that repair with adjuvant materials was better and more effective; nevertheless, use of adjuvant materials resulted in longer duration of surgery and more peri-operative bleeding when compared with the control group, but no significant differences were observed between the two groups regarding visceral injury, postoperative pain, urinary tract infection rate, new stress incontinence and new dyspareunia.

Conclusion

Adjuvant material is worthy of clinical popularization, especially the biological graft type because of its lower anatomy failure rate and no difference in safety compared with the control group. However, exposure to adjuvant materials and erosion rate are high, which are the most important aspects to be improved.

Keywords

Anterior vaginal wall prolapse Repair Adjuvant materials Efficacy Safety 

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Hu Min
    • 1
  • Hong Li
    • 1
  • Li Bingshu
    • 1
  • Cheng Yanxiang
    • 1
  • Chen Lu
    • 1
  • Sun Qing
    • 1
  • Zhu Xuejiao
    • 1
  • Wu Wenying
    • 1
  • Wu Debin
    • 1
  • Hong Shasha
    • 1
  • Ding Wenjuan
    • 1
  • Min Jie
    • 1
  • Zhang Xiaohong
    • 1
  • Guo Wenjun
    • 1
  • Chen Jianhua
    • 1
  • Liu Qian
    • 1
  • Liu Yuling
    • 1
  1. 1.Department of Gynecology and ObstetricsRenmin Hospital of Wuhan UniversityWuhanChina

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