Archives of Gynecology and Obstetrics

, Volume 286, Issue 5, pp 1261–1267 | Cite as

The impact of human papillomavirus (HPV) types 6, 11 in women with genital warts

  • Mahin Jamshidi
  • Mohammad Shekari
  • Abdol Azim Nejatizadeh
  • Keyanoush Malekzadeh
  • Mahnaz Baghershiroodi
  • Parivash Davudian
  • Farzaneh Dehghan
  • Froogh Jamshidi
Gynecologic Oncology



Human papillomaviruses (HPV) are etiologically associated with the development of virtually all genital warts. HPV-6 and HPV-11 are the most commonly detected HPV genotypes, but at least 20 other HPV genotypes have occasionally been found in genital wart tissue specimens.

Study design

The aim of this study was to determine from 100 genital wart tissue specimens collected from female patients using multiplex gap-PCR technique the prevalence of various genital HPV among women with HPV genital warts in south of Iran. 100 genital wart tissue specimens were tested for the presence of HPV PG5/PG6 and also for HPV type using polymerase chain reaction (PCR).


Based on the collected data, 73 (73 %) samples were detected positive for HPV DNA and 23 (23 %) samples out of 100 samples were detected negative for HPV DNA. 49 (49 %) and 67 (67 %) of patients were detected positive for HPV type 6 and 11, respectively. There was a significant association between marital status and HPV genotype 6 (OR = 0.51, 95 % CI = 0.37–0.70, P = 0.01). Nevertheless, no significant association was found between marriage and HPV genotype 11 (OR = 0.85, 95 % CI = 0.58–1, 24, P = 0.7). Similarly, this result was demonstrated, in combined marriage and HPV-general (OR = 0.80, 95 % CI = 0.62–0.05, P = 0.4).


Concerning the prevalence of HPV in our study, determination of genital HPV prevalence and multiple infections among the normal population of women of Hormozgan Province is recommended.


Human papillomavirus Genital warts PCR Typing 


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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Mahin Jamshidi
    • 2
  • Mohammad Shekari
    • 1
    • 2
  • Abdol Azim Nejatizadeh
    • 1
    • 2
  • Keyanoush Malekzadeh
    • 1
  • Mahnaz Baghershiroodi
    • 1
  • Parivash Davudian
    • 2
  • Farzaneh Dehghan
    • 1
  • Froogh Jamshidi
    • 3
  1. 1.Research Center for Molecular MedicineHormozgan University of Medical SciencesBandar-AbbasIran
  2. 2.Infections Research CenterHormozgan University of Medical SciencesBandar-AbbasIran
  3. 3.Dermatology Private ClinicBandar-AbbasIran

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