Archives of Gynecology and Obstetrics

, Volume 285, Issue 6, pp 1593–1597

A modified anterior compartment reconstruction and Prolift-a for the treatment of anterior pelvic organ prolapse: a non-inferiority study

General Gynecology

DOI: 10.1007/s00404-011-2200-7

Cite this article as:
Yang, X. & Li, H. Arch Gynecol Obstet (2012) 285: 1593. doi:10.1007/s00404-011-2200-7



To evaluate, in terms of efficacy and safety, a modified anterior compartment reconstruction procedure for anterior pelvic organ prolapse (POP).


The patients were assigned to two groups according to their individual willingness and economical condition, of whom 68 were treated with the modified procedure and 37 with the ‘Prolift-a’ procedure. The objective cure rate was defined by 0 or I according to POP-Q, which was detected by non-inferiority test between the two groups.


The cure rates were found to be 94.1% (64/68) in the modified group and 97.3% (36/37) in the Prolift-a group, respectively. No significant difference was found between these two groups in the cure rate by non-inferiority test (u = 2.252, P = 0.012). The blood loss and hospitalization costs were significantly lower in the modified group than the Prolift-a group (P < 0.05), while other clinical parameters showed no significant difference between the two groups (P > 0.05).


Both the modified total pelvic reconstruction and Prolift-a operations are safe, efficacious and minimally invasive surgical treatments, while the modified procedure is relatively inexpensive, which has great perspective of clinical application in developing countries.


Modified total pelvic reconstruction Prolift-a procedure Pelvic organ prolapse Surgical treatment 

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  1. 1.Department of Obstetrics and GynecologyTongji Hospital of Tongji UniversityShanghaiChina

Personalised recommendations