Archives of Gynecology and Obstetrics

, Volume 285, Issue 6, pp 1517–1521 | Cite as

Outcomes of pregnancies complicated by hyperemesis gravidarum

  • Oguzhan Kuru
  • Serhat Sen
  • Ozgur Akbayır
  • B. Pinar Cilesiz Goksedef
  • Mehmet Özsürmeli
  • Erkut Attar
  • Halil Saygılı
Maternal-Fetal Medicine



To evaluate maternal and fetal outcomes among women with hyperemesis gravidarum (HG).


In a university hospital and a research and training hospital, a retrospective cohort study was conducted among women with singleton deliveries between 2003 and 2011. Maternal outcomes evaluated included gestational diabetes, pregnancy-induced hypertension, cesarean delivery. Neonatal outcomes also determined were 5-min Apgar score of less than 7, low birth weight, small for gestational age (SGA), preterm delivery, fetal sex, and stillbirth.


There were no statistical differences in the mean of age, parity, the number of artificial pregnancy, and smoking between two groups. Infants from HG pregnancies manifested similar birth weight (3,121.5 ± 595.4 vs. 3,164 ± 664.5 g) and gestational age (38.1 ± 2.3 vs. 38.1 ± 2.6 weeks), relative to infants from the control group (p = 0.67 and 0.91, respectively). In addition, no statistical significant differences were found in the rates of SGA birth, preterm birth, gestational diabetes, pregnancy-induced hypertension, and adverse fetal outcome between two groups (p > 0.05). Cesarean delivery rates were similar in two groups (31.9% in hyperemesis group vs. 27% in control group, p = 0.49). Comparing the gender of the newborn baby and Apgar scores less than 7 at 5 min, there were no statistically significant differences between two groups (p = 0.16 and 0.42, respectively).


Hyperemesis gravidarum is not associated with adverse pregnancy outcomes.


Hyperemesis gravidarum Pregnancy Fetal outcome Maternal outcome 


Conflict of interest

We declare that we have no conflict of interest.


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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Oguzhan Kuru
    • 1
  • Serhat Sen
    • 2
  • Ozgur Akbayır
    • 3
  • B. Pinar Cilesiz Goksedef
    • 4
  • Mehmet Özsürmeli
    • 5
  • Erkut Attar
    • 5
  • Halil Saygılı
    • 5
  1. 1.Department of Obstetrics and GynecologyKanuni Sultan Süleyman Research and Training HospitalIstanbulTurkey
  2. 2.Department of Obstetrics and GynecologySüleymaniye Research and Training HospitalIstanbulTurkey
  3. 3.Kanuni Sultan Süleyman Research and Training HospitalIstanbulTurkey
  4. 4.Department of Obstetrics and GynecologyHaseki Research and Training HospitalIstanbulTurkey
  5. 5.Department of Obstetrics and Gynecology, Istanbul Medical FacultyIstanbul UniversityIstanbulTurkey

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