Recurrent endometrial stromal sarcoma in the cecum causing intussusception
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Abstract
Introduction
Most endometrial stromal sarcomas (ESS) develop recurrent disease at pelvis and lung. Recurrent ESS in the cecum causing intussusception is a rare but emergent phenomenon.
Case report
After initial surgical treatment in 1997, a 41-year-old female developed recurrent ESS in the cecum causing ileo-colic intussusception in 2008, which were operated with right hemicolectomy. The patient was then treated with progestin for 2 years to date. She has since been disease-free.
Conclusion
This case report emphasizes the importance of long-term follow-up and initial surgical treatment of ESS and suggests systemic hormonal therapy in case of recurrence.
Keywords
Endometrial stromal sarcoma Extrauterine Intussusception RecurrenceNotes
Conflict of interest statement
None.
References
- 1.Major FJ, Blessing JA, Silverberg SG et al (1993) Prognostic factors in early-stage uterine sarcoma. A Gynecologic Oncology Group study. Cancer 71:1702–1709PubMedGoogle Scholar
- 2.D’Angelo E, Prat J (2010) Uterine sarcomas: a review. Gynecol Oncol 116:131–139PubMedCrossRefGoogle Scholar
- 3.Lax SF (2007) Molecular genetic changes in epithelial, stromal and mixed neoplasms of the endometrium. Pathology 39:46–54PubMedCrossRefGoogle Scholar
- 4.Tavassoli F, Devilee P (2003) Pathology and genetics of tumours of the breast and female genital organs. In: World Health Organization classification of tumours. IARC Press, LyonGoogle Scholar
- 5.Tavassoli FA, Norris HJ (1981) Mesenchymal tumours of the uterus. VII. A clinicopathological study of 60 endometrial stromal nodules. Histopathology 5:1–10PubMedCrossRefGoogle Scholar
- 6.Sutton GP, Stehman FB, Michael H, Young PC, Ehrlich CE (1986) Estrogen and progesterone receptors in uterine sarcomas. Obstet Gynecol 68:709–714PubMedGoogle Scholar
- 7.Chu MC, Mor G, Lim C, Zheng W, Parkash V, Schwartz PE (2003) Low-grade endometrial stromal sarcoma: hormonal aspects. Gynecol Oncol 90:170–176PubMedCrossRefGoogle Scholar
- 8.Boardman CH, Webb MJ, Jefferies JA (2000) Low-grade endometrial stromal sarcoma of the ectocervix after therapy for breast cancer. Gynecol Oncol 79:120–123PubMedCrossRefGoogle Scholar
- 9.Huang BY, Warshauer DM (2003) Adult intussusception: diagnosis and clinical relevance. Radiol Clin North Am 41:1137–1151PubMedCrossRefGoogle Scholar
- 10.Reich O, Regauer S (2007) Hormonal therapy of endometrial stromal sarcoma. Curr Opin Oncol 19:347–352PubMedCrossRefGoogle Scholar
- 11.Bal A, Mohan H, Aulakh R, Huria A (2008) Endometrial stromal lesions: a morphological and immunohistochemical study of short series. Arch Gynecol Obstet 277:21–24PubMedCrossRefGoogle Scholar
- 12.Aubry MC, Myers JL, Colby TV, Leslie KO, Tazelaar HD (2002) Endometrial stromal sarcoma metastatic to the lung: a detailed analysis of 16 patients. Am J Surg Pathol 26:440–449PubMedCrossRefGoogle Scholar
- 13.Dahhan T, Fons G, Buist MR, Ten Kate FJ, van der Velden J (2009) The efficacy of hormonal treatment for residual or recurrent low-grade endometrial stromal sarcoma. A retrospective study. Eur J Obstet Gynecol Reprod Biol 144:80–84PubMedCrossRefGoogle Scholar
- 14.Leath CA III, Huh WK, Hyde J Jr et al (2007) A multi-institutional review of outcomes of endometrial stromal sarcoma. Gynecol Oncol 105:630–634PubMedCrossRefGoogle Scholar
- 15.Amant F, Coosemans A, Debiec-Rychter M, Timmerman D, Vergote I (2009) Clinical management of uterine sarcomas. Lancet Oncol 10:1188–1198PubMedCrossRefGoogle Scholar
- 16.Kim WY, Lee JW, Choi CH et al (2008) Low-grade endometrial stromal sarcoma: a single center’s experience with 22 cases. Int J Gynecol Cancer 18:1084–1089PubMedCrossRefGoogle Scholar
- 17.Thomas MB, Keeney GL, Podratz KC, Dowdy SC (2009) Endometrial stromal sarcoma: treatment and patterns of recurrence. Int J Gynecol Cancer 19:253–256PubMedCrossRefGoogle Scholar
- 18.Amant F, Moerman P, Cadron I, Neven P, Berteloot P, Vergote I (2003) The diagnostic problem of endometrial stromal sarcoma: report on six cases. Gynecol Oncol 90:37–43PubMedCrossRefGoogle Scholar
- 19.Li N, Wu LY, Zhang HT, An JS, Li XG, Ma SK (2008) Treatment options in stage I endometrial stromal sarcoma: a retrospective analysis of 53 cases. Gynecol Oncol 108:306–311PubMedCrossRefGoogle Scholar
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